: Anxiety is the main cause psychiatric counseling in CVCU. In patient with acutemyocardial infarction, anxiety is one of the circumtances that could give rise to the physicalchanges, as wall as psychological. There are several factors associated with the level ofanxiety that age, education level, sosio economic status, and experience. The purpose of thisresearch to determinan, factor\u27s assosiated with the level of anxiety in patient acutemyocardial infarction in CVCU room of RSUP. Prof. Dr. R. Kandou Manado. Research\u27sdesign has used cross sectional design and the data are collected from respondens bykuesioner and observation sheet. The Samples in this research was taken with total samplingtechnique with 30 respondents as sample. The result of the research using atest of á < 0,05.The conclusion of this research is a relationship between age, education level, socioeconomic status level of experience with anxiety. Suggestion as reference material for thedevelopment of future research with regard to the factors associated with the level of anxietyin patien with acute myocardial infarction. For example, long day care, family support,medical diagnostic, and another etc