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A Green Synthesis of Silver Gel Using Tannic Acid , its Characterization and Antibacterial Activity

Abstract

摘要 研究目的: 纳米银的绿色合成是近年来纳米材料研究的热点之一,现有关于纳米银的制备方法和抗菌性能研究尚缺乏统一标准。单宁酸制备纳米银凝胶是一种简便高效的方法,但其抗菌性能优劣和能否将其应用于临床治疗,国内外未见相关报道。本实验采用一种简便高效的方法制备出稳定性好和粒径均匀的单宁酸银凝胶,并对单宁酸银凝胶进行多种表征分析。在表征单宁酸银相关化学结构性质的基础上,制备出三组不同数量级别的单宁酸银抗菌凝胶,采用MTT法对其进行抗菌性能测定,优化出抗菌最佳浓度,探讨了单宁酸银凝胶对四种不同细菌的抗菌效果,深入研究单宁酸银浓度与抗菌效果的量效关系,为单宁酸银凝胶的临床抗菌应用提供理论依据。 ...Abstract Objective: The green synthesis of silver nanoparticles have attracted attention among the development of nanomaterials, while there exists no uniform standards on their preparation and antibacterial study. Among the various options, the synthesis of silver nanoparticles using tannic acid is one of the most effective method. Though it’s still a question whether the silver nanoparticles ...学位:医学硕士院系专业:医学院_外科学学号:2452012115316

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