Effect of multi-devascularization combined with Curcumin perfusion in the treatment of hepatic VX2 carcinoma in rabbit and on the residual carcinoma angiogenesis
目的：研究姜黄素和肝脏周围防粘连隔离膜包裹对经肝动脉、门静脉栓塞治疗VX2肝癌兔的肝功能和生存期的影响；碘化油栓塞肿瘤血管后的残癌组织内血管新生旺盛，本实验探讨姜黄素和肝周防粘连隔离膜包裹对栓塞后残癌组织血管新生的影响。 方法：40只新西兰大白兔随机分成4组，开腹接种法建立VX2肝癌模型。两周后开腹行肝动脉、门静脉置管术，其中B组、D组手术置管同时行肝周防粘连隔离膜包裹隔离术。手术一周后通过留置化疗泵给药，A组、B组：单纯碘化油栓塞剂，C组、D组：姜黄素和栓塞剂混合乳剂。即A组：肝动脉、门静脉置管+栓塞剂（对照组）；B组：肝动脉、门静脉置管+肝周生物膜包裹+栓塞剂（多途径血供阻断组）；C组：...AIM: To study the influence of the curcumin and anti-adhesion membrane on the liver function and survival time after embolization via hepatic artery and portal vein in rabbits with VX2 liver cancer. After the embolismed by iodinate oil , the residual tumor cell will express more VEGF and grow more new blood vessels. In this experiment of curcumin and anti-adhesion membrane, we will discuss how the...学位：医学硕士院系专业：医学院_外科学学号：2452012115318
