目的：评估脑外伤合并骨折后血清IL-10、TNF-α的含量，IL-10是否对骨折的愈合有促进作用，从而评价脑外伤促进骨折愈合与血清中高IL-10的关系。 方法：选取120只3月龄SD雄性大鼠，体重为195-210g。按照随机数字表法，分为4组，每组30只，分别作以下处理：A组：脑外伤合并股骨骨折组；B组：单纯脑外伤组；C组：单纯股骨骨折组，腹腔注射IL-10蛋白（10μg/kg•d）；D组：单纯股骨骨折组，腹腔注射PBS溶液（1ml）。连续6周观察A组和B组大鼠一般情况，并评估颅脑损伤程度。伤后第6小时、第24小时和第48小时，ELISA法测定A组和B组血清中IL-10、TNF-...Objects：To evaluate the serum IL-10 and TNF-α after trauma brain injury combined fracture. IL - 10 whether have a promoting effect on the healing of bone fracture. Methods：120 3-month-old male SD rats (weight 195-210g) were randomly divided into 4 groups according to random number table. Each group has 30 rats. They were dealed with the 4 methods as follows: Group A: trauma brain injury combined ...学位：医学硕士院系专业：医学院_外科学学号：2452013115350
