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A MRI study of white matter changes in mesial temporal lobe epilepsy patients

Abstract

目的 运用基于体素的形态学测量(voxel-basedmorphometry,VBM)及基于纤维束骨架的空间统计方法(tract-basedspatialstatistics,TBSS)对内侧颞叶癫痫(mesialtemporallobeepilepsy,MTLE)患者全脑白质体积和白质纤维束弥散张量成像(diffusiontensorimaging,DTI)参数进行分析,并探讨MTLE患者脑白质结构改变与认知水平的关系。 材料和方法 选取24例右利手MTLE患者,其中左侧MTLE12例,右侧MTLE12例,另招募性别、年龄及受教育程度与之相匹配的12例健康志愿者作为对照组,使用西门子3...Objective The study was designed to investigate the changes of white matter volume in mesial temporal lobe epilepsy (MTLE) by using voxel-based morphometry (VBM) method,to analyze the diffusion tensor imaging (DTI) parameters of white matter by using tract-based spatial statistics (TBSS) method. Explore the relationship between white matter changes and cognition in MTLE patients. Materials and ...学位:医学硕士院系专业:医学院_影像医学与核医学学号:2452012115322

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