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Asparagus Oligosaccharide’s Purification and Protection of Acute Alcoholic Liver Injury in Kunming Mice

Abstract

寡糖具有抗病毒、抗肿瘤、抗氧化、免疫调节等生物活性,是一种高活性物质,在医药和功能性食品领域显示了巨大的应用前景。与其它来源于植物、几丁质的寡糖相比,目前来源于海藻的寡糖尚未得到大规模开发。本研究前期工作中建立了利用微生物与龙须菜(Gracikarialemaneifarmis)共培养,一步法获得寡糖的方法,简化了生产步骤,降低了成本,并开展了龙须菜寡糖的各项活性研究与开发。本文研究了龙须菜寡糖的纯化方法,并研究其在动物生长、急性酒精肝损伤保护等方面的生理活性。 首先对龙须菜寡糖的纯化制备进行研究。通过微生物酶解法对龙须菜进行降解提取寡糖,通过超滤浓缩、干燥等步骤得到粗品(Soe-I),然后...Recent studies have shown that red algae asparagus (Gracikaria lemaneifarmis) are rich of oligosaccharides, which may possess numerous biological activities including antiviral, anti-tumor, anti-oxidation and immune regulation activities, making them promising functional foods in pharmaceutical and food industry. In this study, red algae asparagus (Gracikaria lemaneifarmis) was biodegraded using m...学位:理学硕士院系专业:生命科学学院_微生物学学号:2162012115238

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