flap核酸内切酶FEN1（flapendonuclease1）是RAD2家族的一种能够识别特异底物结构的核酶。FEN1具有三种酶活性：flap核酸内切酶（FlapEndonuclease,FEN）活性、5’核酸外切酶（5’-Exonuclease,EXO）活性和缺口依赖的核酸内切酶（GapEndonuclease,GEN）活性，在DNA复制、修复以及维持端粒稳定性等方面发挥着重要作用。人们对FEN1在哺乳动物、酵母中的功能已经有了深入了解，但是拟南芥中尚无相关研究。 我们在筛选遮荫反应相关基因的突变体时筛到了一个sav6（shadeavoidance6）突变体，表现为下胚轴和根短小。通过图...FEN1 (Flap endonuclease1) belongs to Rad2 nuclease family,it recognizes the DNA substrate with special structure. It possesses 3 kinds of enzyme activity: flap endonuclease activity, exonuclease activity and gap endonuclease activity. It is required for several DNA metabolic pathways, including DNA replication, repair and maintenance of telomere stability. Despite the wealth information available ...学位：理学博士院系专业：生命科学学院_生物化学与分子生物学学号：2162010015390
