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Noncovalent functionalization of two-dimensional graphene analogues for biomedical applications

Abstract

类石墨烯二维材料(2D-GAs,比如过渡金属硫化物纳米片、g-C3N4、Bi2Se3和黑磷等)由于其独特的成分、结构、理化性质和良好的生物相容性,在生物医学领域展现出前所未有的优势。2D-GAs的制备、表面功能化以及在纳米生物医学领域的应用是目前的研究热点,引起了材料、化学、物理、生物、医学等各个领域科学家的广泛兴趣。 本文对三种2D-GAs(Bi2Se3、MoS2和黑磷)分别进行了表面非共价功能化,探索了这三种2D-GAs在纳米生物医学中的应用。本文主要研究了以下几方面的内容: 一.探索了2D-硒化铋的表面功能化及其用于阻止Aβ1-42聚集。制备了血红素稳定的少层硒化铋(Bi2Se3),...Biocompatible two-dimensional (2D) graphene analogues (e.g., transition metal dichalcogenides nanosheets, g-C3N4, Bi2Se3, phosphorene, etc.), which are referred to as 2D-GAs, have emerged as a new unique family of nanomaterials that show unprecedented advantages and superior performances in biomedicine due to their unique compositional, structural and physicochemical features. Preparation, functio...学位:理学博士院系专业:材料学院_高分子化学与物理学号:2072013015363

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