Architectural Support for Medical Imaging

Abstract

Advancements in medical imaging research are continuously providing doctors with better diagnostic information, removing the need for unnecessary surgeries and increasing accuracy in predicting life-threatening conditions. However, newly developed techniques are currently limited by the capabilities of existing computer hardware, restricting them to expensive, custom-designed machines that only the largest hospital systems can afford or even worse, precluding them entirely. Many of these issues are due to existing hardware being ill-suited for these types of algorithms and not designed with medical imaging in mind. In this thesis we discuss our efforts to motivate and democratize architectural support for advanced medical imaging tasks with MIRAQLE, a medical image reconstruction benchmark suite. In particular, MIRAQLE focuses on advanced image reconstruction techniques for 3D ultrasound, low-dose X-ray CT, and dynamic MRI. For each imaging modality we provide a detailed background and parallel implementations to enable future hardware development. In addition to providing baseline algorithms for these workloads, we also develop a unique analysis tool that provides image quality feedback for each simulation. This allows hardware designers to explore acceptable image quality trade-offs in algorithm-hardware co-design, potentially allowing for even more efficient solutions than hardware innovations alone could provide. We also motivate the need for such tools by discussing Sonic Millip3De, our low-power, highly parallel hardware for 3D ultrasound. Using Sonic Millip3De, we illustrate the orders-of-magnitude power efficiency improvement that better medical imaging hardware can provide, especially when developed with a hardware-software co-design. We also show validation of the design using a scaled-down FPGA proof-of-concept and discuss our further refinement of the hardware to support a wider range of applications and produce higher frame rates. Overall, with this thesis we hope to enable application specific hardware support for the critical medical imaging tasks in MIRAQLE to make them practical for wide clinical use.PHDComputer Science & EngineeringUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttps://deepblue.lib.umich.edu/bitstream/2027.42/137105/1/rsamp_1.pd