Abergel, Armand

Alric, Laurent

Amaddeo, Giuliana

Amzal, Rachida

Andreani, Tony

André-Garnier, Elisabeth

Angoulevant, Bénédicte

Antonini, Teresa

Anty, Rodolphe

Archambeaud, Isabelle

Asselah, Tarik

Bai, Roxane

Bailly, François

Barbereau, Didier

Bardou, Marc

Barraud, Hélène

Barrault, Camille

Barré, Tangui

Baumert, Thomas

Benjamin, Buchard

Bensenane, Mouni

Bernard, Marie-Albertine

Billaud, Eric

Bonnet, Delphine

Bourlière, Marc

Boursier, Jérôme

Boutoille, David

Boyer, Nathalie

Brener, Audrey

Brigitte, Chanteranne

Bronowicki, Jean-Pierre

Brulé, Séverine

Bureau, Christophe

Bureau, Morgane

Cales, Paul

Canva, Valérie

Carrat, Fabrice

Carrier, Paul

Carrieri, Patrizia

Castelnau, Corinne

Catherine, Lucie

Causse, Xavier

Chazouillières, Olivier

Chevalier, Caroline

Chevance, Azeline

Coilly, Audrey

Conroy, Guillaume

Costes, Laurent

d'Alteroche, Louis

Debette-Gratien, Maryline

Decaens, Thomas

Dharancy, Sébastien

Di Beo, Vincent

Dieuleveult, Barbara De

Doffoel, Michel

Dorival, Céline

Duclos Vallée, Jean-Charles

Elkrief, Laure

Faure, Marine

Fontaine, Hélène

Foucher, Juliette

Froissart, Bruno

Ganne, Nathalie

Geist, Claire

Gelsi, Eve

Gelu-Simeon, Moana

Giuily, Nathalie

Goria, Odile

Gournay, Jérôme

Grando-Lemaire, Véronique

Guyader, Dominique

Habersetzer, François

Habes, Sarah

Hagège, Hervé

Hammeche, Saloua

Hassani-Nani, Sarah

Hilleret, Marie-Noelle

Hiriart, Jean-Baptiste

Hubert, Isabelle

Hucault, Lucie

Irlès-Depé, Marie

Jaillais, Anaïs

Jezequel, Caroline

Labarrière, Damien

Lafrance, Marie-Josée

Laligant, Anne

Lannes, Adrien

Larrey, Dominique

Lassailly, Guillaume

Latournerie, Marianne

Ledinghen, Victor De

Lefebvre, Maeva

Lemaitre, Elise

Leroy, Vincent

Loustaud-Ratti, Véronique

Louvet, Alexandre

Lunel, Françoise

M'Bouyou, Jancell

Marcellin, Fabienne

Mathurin, Philippe

International audienceBackground: Chronic hepatitis B virus (HBV) infection may evolve into cirrhosis and hepatocellular carcinoma, and this progression may be accelerated by specific risk factors, including overweight and obesity. Although evidence for a protective effect of cannabis use on elevated body weight has been found for other populations, no data are available for HBV-infected patients.Aims: We aimed to identify risk factors (including cannabis use) for overweight and obesity in patients with HBV chronic infection.Methods: Using baseline data from the French ANRS CO22 Hepather cohort, we performed two separate analyses, one using “central obesity” (based on waist circumference) and the other “overweight” and “obesity” (based on body mass index) as outcomes. Logistic and multinomial regressions were used to model central obesity and overweight/obesity, respectively.Results: Among the 3706 patients in the study population, 50.8% had central obesity, 34.7% overweight, and 14.4% obesity. After multivariable adjustment, current cannabis use was associated with a 59% lower risk of central obesity compared with no lifetime use (adjusted odds ratio [95% CI]: 0.41 [0.24 to 0.70]). It was also associated with a 54% and 84% lower risk of overweight (adjusted relative risk ratio [95% CI]: 0.46 [0.27 to 0.76]) and obesity (0.16 [0.04 to 0.67]), respectively.Conclusions: Cannabis use was associated with lower risks of overweight and obesity in patients with HBV chronic infection. Future studies should test whether these potential benefits of cannabis and cannabinoid use translate into reduced liver disease progression in this high-risk population

Pol, Stanislas

Ramier, Clémence

Serfaty, Lawrence

Protopopescu, Camelia

Payssan-Sicart, Virginie

Pomes, Chloe

Zoulim, Fabien

Maynard, Marianne

Raffi, François

Scoazec, Giovanna

Rousseaud, Emilie

Vallet-Pichard, Anaïs

Sogni, Philippe

Si Ahmed, Si Nafa

Oules, Valérie

Tran, Albert

Truchi, Régine

Thabut, Dominique

Moussali, Joseph

Ouarani, Brahim

Nahon, Pierre

Ulker, Betul

Rabot, Aline

Renard, Isabelle

Mutter, Catherine

Simo-Noumbissie, Pauline

Razi, Esma

Nani, Abdelbasset

Pageaux, Georges-Philippe

Meszaros, Magda

Metivier, Sophie

Morales, Thibault

Peron, Jean Marie

Robic, Marie Angèle

Zarski, Jean-Pierre

Riachi, Ghassan

Paris, Fatima

Montialoux, Hélène

HAL AMU

Cannabis Use Is Inversely Associated with Overweight and Obesity in Hepatitis B Virus-Infected Patients (ANRS CO22 Hepather Cohort)

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HAL-IRD

Cannabis Use Is Inversely Associated with Overweight and Obesity in Hepatitis B Virus-Infected Patients (ANRS CO22 Hepather Cohort)

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