Fantke, Peter

Jolliet, Olivier

McKone, Thomas E

Vigon, Bruce

Exposure to fine particulate matter (PM2.5) pollution is a major contributor to human disease burden as continuously shown in the Global Burden of Disease study series. Exposures to PM2.5 concentration outdoors and indoors contribute almost equally to this burden. Despite the importance, health impacts from exposure to PM2.5 are often excluded from life cycle impact assessment (LCIA) characterization profiles. This is in large part because of the lack of well-vetted harmonized guidance about how to consistently assess the exposures and impacts of indoor and outdoor emissions of PM2.5 and its precursors. We present a framework for calculating characterization factors for indoor and outdoor emissions of primary PM2.5 and secondary PM2.5 precursors, and a roadmap for further refining this modelling framework for operational use in LCIA. The framework was developed over the last three years by a task force convened under SETAC/UNEP auspices. A recent SETAC Pellston Workshop® was convened to formalize guidance and methods for estimating the health impacts associated with PM2.5 exposure and to recommend PM2.5 characterization factors for application in life cycle assessment. The framework involves three stages–analyzing PM2.5 fate and exposure (including indoor and outdoor urban/rural nvironments), modeling exposure-response, and the integration of exposure-response and PM2.5 exposure reflecting population and location characteristics. Our exposure model is organized as a mass balance matrix that tracks the global fate of primary PM2.5 and secondary PM2.5 precursor emissions (both indoors and outdoors) as an embedded system of ompartments including urban environments, rural environments, and indoor environments within urban and rural areas. After presenting the model structure, we will review initial results and will present geographic variability, discuss key uncertainties, and evaluate our model using results from other models and concentration measurements

Online Research Database In Technology

                       General rights Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.  • Users may download and print one copy of any publication from the public portal for the purpose of private study or research. • You may not further distribute the material or use it for any profit-making activity or commercial gain • You may freely distribute the URL identifying the publication in the public portal   If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.     Downloaded from orbit.dtu.dk on: Dec 18, 2017Characterizing health impacts from indoor and outdoor exposure to fine particulatesVigon, Bruce; Fantke, Peter; McKone, Thomas E; Jolliet, OlivierPublished in:Society of Environmental Toxicology and chemistry Asia/Pacific 2016 ConferencePublication date:2016Link back to DTU OrbitCitation (APA):Vigon, B., Fantke, P., McKone, T. E., & Jolliet, O. (2016). Characterizing health impacts from indoor and outdoorexposure to fine particulates. In Society of Environmental Toxicology and chemistry Asia/Pacific 2016ConferenceI116CHARACTERIZING HEALTH IMPACTS IN LIFE CYCLE ASSESSMENT FROM EXPOSURE TO FINE PARTICULATESBruce Vigon1, *,	Peter	Fantke2, Thomas McKone3 and Olivier Jolliet4  1 Society of Environmental Toxicology and Chemistry (SETAC), 229 S. Baylen St., Pensacola FL 32502USA,  email: bruce.vigon@setac.org2 Technical University of Denmark, Produktionstorvet 426, Kgs. Lyngby, Capital Region, 2800   Denmark,  email: pefan@dtu.dk3 University of California, 50 University Hall, #7360, Berkeley, CA 94720-7360 USA,email:temckone@lbl.gov4 University of Michigan, 3890 Tremont Place, Ann Arbor, MI 48105 USA, email:ojolliet@umich.eduExposure	to	fine	particulate	matter	(PM2.5)	pollution	is	a	major	contributor	to	human	disease	burden	as	continuously	shown in the Global Burden of Disease study series. Exposures to PM2.5 concentration outdoors and indoors contribute almost equally to this burden. Despite the importance, health impacts from exposure to PM2.5 are often excluded from life	cycle	 impact	assessment	(LCIA)	characterization	profiles.	This	 is	 in	 large	part	because	of	 the	 lack	of	well-vetted	harmonized guidance about how to consistently assess the exposures and impacts of indoor and outdoor emissions of	PM2.5	and	its	precursors.	We	present	a	framework	for	calculating	characterization	factors	for	 indoor	and	outdoor	emissions	 of	 primary	 PM2.5	 and	 secondary	 PM2.5	 precursors,	 and	 a	 roadmap	 for	 further	 refining	 this	 modelling	framework	for	operational	use	in	LCIA.	The	framework	was	developed	over	the	last	three	years	by	a	task	force	convened	under SETAC/UNEP auspices. A	 recent	 SETAC	Pellston	Workshop®	was	 convened	 to	 formalize	 guidance	 and	methods	 for	 estimating	 the	 health	impacts associated with PM2.5 exposure and to recommend PM2.5 characterization factors for application in life cycle assessment.	The	framework	involves	three	stages	–	analyzing	PM2.5	fate	and	exposure	(including	indoor	and	outdoor	urban/rural environments), modeling exposure-response, and the integration of exposure-response and PM2.5 exposure reflecting	population	and	location	characteristics.	Our	exposure	model	is	organized	as	a	mass	balance	matrix	that	tracks	the global fate of primary PM2.5 and secondary PM2.5 precursor emissions (both indoors and outdoors) as an embedded system of compartments including urban environments, rural environments, and indoor environments within urban and rural areas. After presenting the model structure, we will review initial results and will present geographic variability, discuss	key	uncertainties,	and	evaluate	our	model	using	results	from	other	models	and	concentration	measurements.	Keywords:	1)	Life	cycle	assessment,	2)	particulate	matter,	3)	health	effects,	4)	PM2.5,	5)	 impact	assessment,	6)	air	pollution4B.14B. AIRBORNE PARTICULATE MATTER AND PUBLIC HEALTHAbstracts – Oral Presentation

Characterizing health impacts from indoor and outdoor exposure to fine particulates

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Characterizing health impacts from indoor and outdoor exposure to fine particulates

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