Anvari, B

Elson, D

Annals of Biomedical Engineering

English

Daniel Elson

Bahman Anvari

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Biophotonics in Bioengineering

Spiral - Imperial College Digital Repository

Elson D, Anvari B Biophotonics in bioengineering. Ann Biomed Eng 40(2):250 Feb 2012  Biophotonics in Bioengineering  Biophotonics encompasses the fundamental interactions of light and biological materials.  The field has produced optical imaging, diagnostic and therapeutic devices that have impacted modern medicine. It has provided major advances in biomedical research through development of technologies for high resolution microscopy, and contributed to the progress in molecular labelling through the development of fluorescent proteins, and medically relevant contrast and therapeutic agents.  Many of these interdisciplinary activities have involved bioengineers and have grown out of bioengineering departments.  This special issue of ABME encompasses research papers at the interface of biophotonics and bioengineering which we have solicited from internationally renowned researchers. This includes a total of 19 review articles to introduce the field to a general audience of bioengineers, and the topics have been selected to cover a broad range of biophotonics research areas.   The subjects of endoscopy and tissue optics are covered in reviews by Stoyanov on how computational techniques are being used in surgical vision [ref], and Fantini and Sassaroli who detail the current state of near-infrared optical mammography for breast cancer detection [ref].  The promising diagnostic role of optical spectroscopic techniques are described by Marcu [ref], who has reviewed the applications of fluorescence lifetime imaging for the diagnosis of different tissue pathologies using only naturally occurring fluorophores.  Reviews of how ultrasound and optics may be combined for enhanced imaging are presented by Murray et al. who describe the monitoring of therapeutic responses with acousto-optic imaging [ref], and Sarantopoulos et al. appraise the use of opto-acoustic methods in interventional imaging [ref].  Microscopic methods for imaging cellular and sub-cellular processes from clinical and research perspectives are covered in papers by Maio et al. focusing on optical projection tomographic microscopy, and Perry et al on the use of two photon and second harmonic microscopy [ref].  Finally, we have selected papers on photo- and thermal-therapy that introduce mechanisms through which light may be used for tissue therapy.  Chung et al. describe techniques in low-level laser therapy and how they are being applied to different diseases and tissues.  Chit Yaw et al. examine the use of photosensitizers for photodynamic diagnosis, and the combination of photothermal and photodynamic therapies.  We hope that the papers selected will be of interest to the bioengineering community in general, and thank the investigators for their outstanding contributions.   Optional biographies, may not be necessary, or have enough space.  The issue is guest edited by Daniel Elson and Bahman Anvari.  Daniel Elson obtained a degree in Physics, Imperial College, London in 1999.  This was followed by a Ph.D. in Physics in 2003 supervised by Professor Paul French and entitled ‘Development of Ultrafast Laser Technology and its Application to Fluorescence Lifetime Imaging’.  In 2005 he was appointed as a lecturer in the Institute of Biomedical Engineering, Imperial College London jointly with the Department of Biosurgery and Surgical Technology.  In 2010 he joined the newly launched Hamlyn Centre for Robotic Surgery, where he is currently a senior lecturer in Elson D, Anvari B Biophotonics in bioengineering. Ann Biomed Eng 40(2):250 Feb 2012  surgical imaging in association with the Department of Surgery and Cancer. His laboratory is working to translate promising emerging optical and biophotonics diagnostic imaging and therapy techniques into surgical practice. The laboratory designs, builds and tests optical imaging and spectroscopy instruments that are able to detect diseased tissue states using techniques such as diffuse reflectance spectroscopy, optical coherence tomography and microconfocal endoscopy.  Beyond these core optical imaging research tools, the laboratory is also developing instruments and techniques that can be used in the field of image-guided and robotic assisted surgery.  Dr. Elson is an Associate Editor of the Annals.  Bahman Anvari has a Ph.D. Bioengineering  (1993) from Texas A&M University. He was a Postdoctoral Researcher at the Beckman Laser Institute and Medical Clinic, University of California, Irvine, and later a Research Assistant Professor of Engineering at Harvey Mudd College. He joined the Bioengineering Department at Rice University in 1998 as an Assistant Professor, and became an Associate Professor in 2003. In 2006, Dr. Anvari joined the newly established Department of Bioengineering at University of California, Riverside (UCR) as a Professor. His current research activities are directed towards: (1) construction, characterization, and utilization of multi-functional optical nano-structures in translational research for imaging and phototherapy; and (2) investigation of biophysical properties, particularly nano-electromechanical characteristics of cellular membranes using optical methods. Dr. Anvari is an Associate Editor of the Annals of Biomedical Engineering, and an Editorial Board Member of the Journal of Biomedical Optics. He is an honorary Fellow of the American Association for the Advancement of Science (AAAS) and the American Institute for Medical and Biological Engineering (AIMBE)  

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Biophotonics in Bioengineering

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