Concomitant use of dronedarone with dabigatran in patients with atrial fibrillation in clinical practice.

Abstract

Dronedarone is a strong P-glycoprotein inhibitor with a potential to increase bioavailability of dabigatran. We sought to measure and report plasma concentrations of dabigatran in patients with atrial fibrillation (AF) on concomitant dronedarone treatment