A New Role for E2F-1 in Checkpoint Control

Authors
Publication date
12 September 2003
Publisher
Taylor and Francis
Doi

    Abstract

    In response to DNA damage, E2F-1 is induced and phosphorylated. Phosphorylated E2F-1 can reside in discrete nuclear structures and induce apoptosis, suggesting a unique role for E2F-1 in DNA repair and checkpoint functions

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