The list of species of the larger Brachycera known from Malta is updated according to current classification and nomenclature. All species, including new records, are included except for the Bombyliidae previously recorded by the present author. Here are listed 7 spp of Stratiomyidae, 1 of Vermileonidae, 1 of Rhagionidae, 3 of Tabanidae, 3 of Therevidae, 7 of Asilidae, 6 of Bombyliidae and 2 each of Scenopinidae and Acroceridae. For species recorded here for the first time, all data are given. Each Family is followed by comments on what is known about it locally.peer-reviewe