This Report documents the results obtained by the Working Group on Quantum ChromoDynamics and the Standard Model for the Workshop "Physics at TeV Colliders", Les Houches, France, 21 May - 1 June 2001. The account of uncertainties in Parton Distribution Functions is reviewed. Progresses in the description of multiparton final states at Next-to-Leading Order and the extension of calculations for precision QCD observables beyond this order are summarized. Various issues concerning the relevance of resummation for observables at TeV colliders is examined. Improvements to algorithms of jet reconstruction are discussed and predictions for diphoton and photon pi-zero production at the LHC are made for kinematic variables of interest regarding searches for a Higgs boson decaying into two photons. Finally, several improvements implemented in Monte-Carlo event generators are documented