Gaillard, F

Jacquemont, L

Lazareth, H

Albano, L

Barrou, B

Bouvier, N

Buchler, M

Titeca-Beauport, D

Couzi, L

Delahousse, M

Ducloux, D

Etienne, I

Frimat, L

Garrouste, C

Glotz, D

Grimbert, P

Hazzan, M

Hertig, A

Hourmant, M

Kamar, N

Le Meur, Y

Le Quintrec, M

Legendre, C

Moal, V

Moulin, B

Mousson,

Pouteil-Noble, C

Rieu, P

Ouali, N

Rostaing, L

Thierry, A

Touré, F

Chemouny, J

DELANAYE, Pierre

Courbebaisse, M

Mariat, C

International audienceMultiple days assessments are frequent for the evaluation of candidates to living kidney donation, combined with an early GFR estimation (eGFR). Living kidney donation is questionable when eGFR is &lt;90 ml/min/1.73 m2 (KDIGO guidelines) or 80 ml/min/1.73 m2 (most US centres). However, age-related GFR decline results in a lower eGFR for older candidates. That may limit the number of older kidney donors. Yet, continuing the screening with a GFR measure increases the number of eligible donors. We hypothesized that in-depth screening should be proposed to all candidates with a normal eGFR for age. We compared the evolution of eGFR after donation between three groups of predonation eGFR: normal for age (Sage ) higher than 90 or 80 ml/min/1.73 m2 (S90 and S80, respectively); across three age groups (&lt;45, 45-55, &gt;55 years) in a population of 1825 French living kidney donors with a median follow-up of 5.9 years. In donors younger than 45, postdonation eGFR, absolute- and relative-eGFR variation were not different between the three groups. For older donors, postdonation eGFR was higher in S90 than in S80 or Sage but other comparators were identical. Postdonation eGFR slope was comparable between all groups. Our results are in favour of in-depth screening for all candidates to donation with a normal eGFR for age

Gaillard, F.

Jacquemont, Lola

Lazareth, Hélène

Albano, Laetitia

Barrou, Benoit

Bouvier, Nicolas

Buchler, Mathias

Titeca-Beauport, Dimitri

Couzi, Lionel

Delahousse, Michel

Ducloux, Didier

Etienne, Isabelle

Frimat, Luc

Garrouste, Cyril

Glotz, Denis

Grimbert, Philippe

Hazzan, Marc

Hertig, Alexandre

Hourmant, Maryvonne

Kamar, Nassim

Le Meur, Yann

Le Quintrec, Moglie

Legendre, Christophe

Moal, Valérie

Moulin, Bruno

Mousson, Christiane

Pouteil-Noble, Claire

Rieu, Philippe

Ouali, Nacera

Rostaing, Lionel

Thierry, Antoine

Toure, Fatouma

Chemouny, Jonathan Maurice, M

Delanaye, Pierre

Courbebaisse, Marie

Mariat, Christophe

HAL-HCL

Living kidney donor evaluation for all candidates with normal estimated GFR for age

International audienceMultiple days assessments are frequent for the evaluation of candidates to living kidney donation, combined with an early GFR estimation (eGFR). Living kidney donation is questionable when eGFR is 55 years) in a population of 1825 French living kidney donors with a median follow-up of 5.9 years. In donors younger than 45, postdonation eGFR, absolute- and relative-eGFR variation were not different between the three groups. For older donors, postdonation eGFR was higher in S90 than in S80 or Sage but other comparators were identical. Postdonation eGFR slope was comparable between all groups. Our results are in favour of in-depth screening for all candidates to donation with a normal eGFR for age

Chemouny, Jonathan Maurice,

Hal-Diderot

HAL AMU

HAL - UPEC / UPEM

HAL: Hyper Article en Ligne

HAL-Inserm

Portail HAL Um  (Université de Montpellier)

HAL - Normandie Université

Open Repository and Bibliography - Liège

Transplant International

Living kidney donor evaluation for all candidates with normal estimated GFR for age.

HAL-IRD

https://hal.science/hal-03665050v1/document

Living kidney donor evaluation for all candidates with normal estimated GFR for age.

Abstract

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