Anticorpos anti-VIH1 e VIH2 em doentes com Tuberculose. Experiência de um trabalho realizado ao longo de 3 anos nas regiões de Lisboa, Barreiro e Santarém

Abstract

ABSTRACTSettingPatients with active tuberculosis.ObjectiveTo evaluate the rates of anti-HIV1 and anti-HIV2 antibodies in patients with active Tuberculosis.DesignAnti-HIV antibodies, were searched by ELISA and confirmed by Western blot.ResultsWe studied 767 patients (479 men and 288 women); 671 of them were caucasian, 76 black and 20 from other races. Eighteen of them were intravenous-drug users (IVDU), 35 had been transfused, 630 were heterosexual and in 121 we didn’t obtain data about sexual behaviour; 153 sojourned in Africa for different periods of time; 541 patients (70.5%) had pulmonary tuberculosis, 164 (21.4%) had extrapulmonary tuberculosis, 44 (5,7%) patients presented pulmonary and extrapulmonary tuberculosis and 18 (2.3%) had primary tuberculosis. Fourteen (1.8%) patients bad anti-HIV antibodies: 10 HIV1 and 4 HIV2; all seropositive were heterosexual, one being IVDU; 5 had pulmonary tuberculosis and 9 had extra-pulmonary tuberculosis (including all 4 cases with HIV2).ConclusionsWe found a rate in our population of 1.8% particularly in black patients (3.9%); serum positivity was more frequent in patients with extrapulmonary tuberculosis particularly in HIV2 patients. We advise for systematic screening