Chen, Bangdang

Chen, Xiaocui

Fu, Zhenyan

Gai, Mintao

Li, Xiaomei

Liu, Fen

Ma, xiang

Ma, Yitong

Xie, Xiang

Yang, Yining

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GW26-e2358 Current status regarding the cardiovascular disease-related risk levels among the hypertensive population of different ethnicities in Xinjiang, China 

J O U R N A L O F T H E A M E R I C A N C O L L E G E O F C A R D I O L O G Y , V O L . 6 6 , N O . 1 6 , S U P P L S , 2 0 1 5 C119with 5 YSM and then decreased. Other risk factors of hypertension
were body mass index (BMI), abdominal obesity, a family history of
cardiovascular disease among ﬁrst-degree relatives, a personal history
of diabetes, and high TG.
GW26-e2344
The optimal cutoff point of waist-to-hip ratio for Uyghur population aged
over 35 years in Xinjiang
Abudukeremu, Shuo Pan, Yining Yang, Xiang Ma, Xiaomei Li,
Zhenyan Fu, Ying Huang, Xiang Xie, Fen Liu, Yitong Ma
Department of Cardiology, First Afﬁliated Hospital of Xinjiang Medical
University, Urumqi 830054, China
OBJECTIVES We aimed to explore the appropriate WHR cutoffs to
identify people at high risk of cardiovascular disease of Uygur adults
in Xinjiang.
METHODS The cardiovascular risk survey(CRS) in Xinjiang was con-
ducted from October 2007 to March 2010, using 4-stagestratiﬁed random
sampling method to select 14618 representative participants, and the
questionnaire survey, anthropometric data, blood pressure, serum con-
centration of serum total cholesterol, triglyceride, low density lipopro-
tein (LDL), high density lipoprotein (HDL) and fasting glucose were
documented. A total of 4767 Uyghur people were selected and completed
the study. The present statistical analysis was restricted to the 4657
adults between 35 and 101 years old who had complete anthropometric
data. The sensitivity, speciﬁcity and distance on the receiver operating
characteristic (ROC) curve of different WHR levels predicting risk factors
of cardiovascular disease were calculated. The analysis method of ROC
curve was used to determine the optimum cut-off point of WHR pre-
dicting risk factors of cardiovascular disease.
RESULTS (1) The prevalence of hypertension, hypercholesterolemia
and hypertriglyceridemia were higher with higher WHR for both men
and women. While the prevalence of diabetes, high LDL, low HDL did
not show obvious trend both in men and women.
(2) The shortest distance in the ROC curves for hypertension, dys-
lipidemia, diabetes and 2 of these risk factors suggested a WHR
cutoff of 0.92 for men and 0.90 for women.
CONCLUSIONS Higher WHR cutoffs are needed in the identiﬁcation
of people at high risk of cardiovascular disease among Uygur adults in
Xinjiang.
GW26-e2358
Current status regarding the cardiovascular disease-related risk levels
among the hypertensive population of different ethnicities in Xinjiang,
China
Mintao Gai, Yining Yang, Xiang Xie, Xiaomei Li, xiang Ma, Fen Liu,
Zhenyan Fu, Bangdang Chen, Xiaocui Chen, Yitong Ma
Department of Cardiology, First Afﬁliated Hospital of Xinjiang Medical
University
OBJECTIVES To learn the status of the cardiovascular disease asso-
ciated risk levels among Xinjiang Han, Uygur and Kazakh hyperten-
sive population.
METHODS Using the four stages stratiﬁed random sampling method,
all the data was collected from local residents age large than 18,
subjects information include lifestyle, physical examination and lab-
oratory examination results from 2007 to 2010.
RESULTS There is 15061 subjects accomplish this survey, in which
2654 Han, 1612 Uygur and 2034 Kazakh people diagnosed with hy-
pertension, Most of them were “grade one hypertension”. Cardio-
vascular disease related risk factors respectively in Han, Uygur and
Kazakh, include older age (39.3%, 38.0%, 30.9%), smoking (33.2%,
20.1%, 32.4%), abnormal fasting glucose (10.4%, 6.5%, 8.0%),
abnormal TC (19.4%, 13.6%, 24.7%), obesity (26.0%, 39.8%, 46.3%).
Majority hypertensive people accompany with 1 risk factor. The risk
proportions of low, medium, high and very high in hypertension
population of different ethnicities respectively is Han (19.4%, 34.6%,
18.8%, 27.3%), Uygur (17.7%, 37.6%, 17.3%, 27.4%) and Kazakh (12.5%,
38.0%, 31.1%, 18.3%). Most proportion of hypertension people in high
risk and very high risk situation, the medium risk hypertension pop-
ulation proportion in female were also very large. In the aware group,
the medium risk population is mostly. In the group without therapy,
medium risk, high risk and very high risk proportion were similar
high, The cardiovascular disease risk stratiﬁcation in age, gender,
aware or unaware of disease, medicine therapy or not have signiﬁcant
difference in different ethnicities of hypertension population.
CONCLUSIONS The cardiovascular disease risk-related levels in Xinjiang
hypertension population have difference between Han, Uygur and Kazakhethnicities, most of hypertension population under high risk and very high
risk of situation, especially in those age 60, males population. In female,
medium risk population proportion were also very high.
GW26-e4731
Prevalence of atrial ﬁbrillation and its risk factors in rural China: a cross-
sectional study
Guozhe Sun,1 Liang Guo,1 Xunzhang Wang,2 Hongjie Song,1 Zhao Li,1
Jun Wang,1 Yingxian Sun1
1Department of Cardiovascular Medicine, The First Hospital of China
Medical University, Shenyang, Liaoning 110001, China; 2Heart Institute,
Cedars Sinai Medical Center, Los Angeles 90048, California USA
OBJECTIVES To evaluate the prevalence of atrial ﬁbrillation (AF) in
physical laborers in rural China and identify contributing risk factors.
METHODS A cross-sectional study of 11,956 permanent residents of
Liaoning Province in rural China  35 y of age (primarily physical laborers)
was conducted between January and August 2013 (response rate 85.3%).
All participants completed a questionnaire and underwent a physical
exam, echocardiography and electrocardiography. Blood samples were
drawn for laboratory analyses, and AF was diagnosed on the basis of
history and electrocardiograph ﬁndings. Risk factors for AF were evalu-
ated with a stepwise logistic regression analysis.
RESULTS The prevalence of AF was 1.2% overall, but rose steeply with
age (0.1% in those 35–44 y of age, and 4.6% in those  75 y); there was no
signiﬁcant gender difference at any age. Independent risk factors for AF
were age (odds ratio [OR] 1.89; P < 0.001), diabetes (OR 2.07; P ¼ 0.001),
history of myocardial infarction (OR 5.91; P < 0.001), low left ventricular
ejection fraction (OR 1.85; P ¼ 0.005), and low physical activity (OR 1.72;
P ¼ 0.003), whereas obesity, hypertension, cholesterol and triglyceride
levels, current smoking and drinking, left ventricular hypertrophy, and
family history of AF were not signiﬁcant contributors.
CONCLUSIONS Although the prevalence of AF in physical labors in
rural China is low, age, diabetes, history of myocardial infarction, low
left ventricular ejection fraction, and low physical activity are inde-
pendent risk factors.
GW26-e4777
Differentiation the acute effects of Black Carbon and PM2.5 on blood
pressure during pregnancy
Jing Hua,1 Fuhai Geng,2 Li Peng,2 Zhuo Chun Wu,3 Guanghua Wang1
1Shanghai First Maternity and Infant Hospital, Tongji University School
of Medicine; 2Shanghai Key Laboratory of Meteorology and Health,
Shanghai Meteorological Bureau; 3The department of Health statistics
and social medicine, Fudan University
OBJECTIVES Levels of ambient ﬁne particulate matter (PM2.5) in China
are among the highest in the world. Black carbon (BC) is an important
component of PM2.5, which has been associated more strongly than has
PM2.5 with the adverse health effects. To our knowledge, few studies have
been conducted to differentiate the associations of PM2.5 and black carbon
on blood pressure (BP) and hypertensive disorders of pregnancy (HDP).
We aim to explore acute effects of Black Carbon and PM2.5 on blood
pressure in the third trimester of pregnancy so as to provide clues for
further studies on HDP and air quality indicators in China.
METHODS The health data came from a cohort study on prevalence of
HDP and gestational diabetes in Shanghai City in 2010. The environ-
mental data obtained from Shanghai Key Laboratory of Meteorology
and Health. A total 7408 pregnant women were included in the study.
We applied generalized additive mixed model to examine the asso-
ciations of air pollutants and blood pressure. The exposure variables
were PM2.5, BC on the same day (1-day average) and 3- to 5-day av-
erages, and the outcome variables were systolic blood pressure (SBP),
diastolic blood pressure (DBP) measured in the third trimester. The
nonlinear covariates of daily temperature and humidity were adjusted
by natural cubic regression splines. All statistical analyses were per-
formed using R Statistical Software, version R 2.15.1.
RESULTS In one-pollutant model, after adjustment for maternal age,
nulliparity, multiple birth, BMI at ﬁrst perinatal visit, family history of
hypertension, and other chronic disease, history of abnormal preg-
nancy, and daily temperature and humidity, we found IQR increases
3-day and 5-day average PM2.5 may induce 0.38 mmHg (95% CI, 0.12 to
0.64), 0.30 mmHg (95%CI, 0.03, 0.57) increases in SBP. IQR increases
in 1-day, 3-day and 5-day average BC predicted 0.49 mmHg (95%CI,
0.21 to 0.78), 0.48 mmHg(95% CI,0.19 to 0.76), and 0.50 mmHg (95%
CI,0.21, 0.79) increases in SBP. We also observed the similar ﬁndings
in DBP, 3-day and 5-day average PM2.5 increased 0.52 mmHg (95%CI,
0.07 to 0.98), 0.48 mmHg (95%CI, 0.02, 0.93); and BC increased


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GW26-e2358 Current status regarding the cardiovascular disease-related risk levels among the hypertensive population of different ethnicities in Xinjiang, China

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