M.A. Bisi-Johnson

O.A. Olowe

International Journal of Infectious Diseases

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Studies on bacterial agents of surgical site infection in Osogbo, South Western Nigeria

Bisi-Johnson, M.A.

Olowe, O.A.

Elsevier - Publisher Connector 

Studies on bacterial agents of surgical site infection in Osogbo, South Western Nigeria 

346 16th ICID Abstracts / International Journal of Infectious Diseases 21S (2014) 1–460
factor was smoking. Most important comorbidity was underlying
structural lung diseases.
http://dx.doi.org/10.1016/j.ijid.2014.03.1133
Type: Poster Presentation
Final Abstract Number: 58.029
Session: Bacterial Infections
Date: Saturday, April 5, 2014
Time: 12:45-14:15
Room: Ballroom
Hyperbaric oxygen treatment on diabetic foot
and associated risk factors of lower limb
amputation: Descriptive study
J. Valbuena, P. Burguen˜o, J.L. Teja, J.F. Gutierrez, A.
Arnaiz
hospital marques de valcecilla, Santander, Spain
Background: Approximately 10-15% of diabetic patients
develop diabetic foot (DF), which precede 85% of the lower limb
amputation (LLA). The use of hyperbaric oxygen therapy (HBOT)
has been suggested to encourage ulcer healing thus reducing the
risk of LLA. The objective of this study is to evaluate the efﬁcacy of
HBOT in DF and asses the risk of LLA in this group of patients.
Methods&Materials:Descriptionof thecohortofpatientsdiag-
nosed with DF that received HBOT from 1st of January, 2010 to 31
of May of 2013 in the University Hospital Marques de Valdecilla
(Santander-Spain).
Results: Forty patients with an average age of 61.35 years,
received 16.13 sessions of HBOT. Epidemiological characteristics
of patients were: 92.5% men, 72.5% had hypertension, 57.5% were
non smokers, 40% had chronic renal failure and 30% had polyneu-
ropathy.Averagedevelopment timeof thewoundwas3.92months.
Indication of HBOT was infection in 72.5% of patients (20% due to
chronic osteomyelitis). Wounds were located: 22.5% in calcaneus
and 17.5% in interdigital area. Revascularization treatment of the
lower limb was needed in 47.5% of the patients. Granulation tissue
at the beginning of HBOT was presented in 5% of patients. Wounds
were closed in 8.8% patients at the ﬁrst month, 35.7% at the third
month, 68% at the sixthmonth and79.2% in theﬁrst year after treat-
ment. 35.9% patients needed amputation, with an average of 32.5
days after HBOT. 69.4% patients did not need antibiotherapy. Asso-
ciated risk factors for amputation were the presence of infection
(4.527, p =0.033) and non related-DF returns to the system (10.89,
p =0.001).
Conclusion: Adjunctive HBOT can be valuable for treating
selected cases of hypoxicDF ulcers. In our cohort, HBOTwas used as
adjuvant treatment in 40 cases, most of them with vascular injury.
We observe increasing rates of granulation tissue after HBOT that
persists in the ﬁrst year of follow up. Risk of amputation (35.9%) is
lower than shown by other series. However, it still remains high,
mostly associated to the presence of infection and need of readmis-
sion to hospital. However a multidisciplinary approach and further
long-term evaluation are needed to deﬁne patient selection and
the role of HBOT in the treatment of DFTORS for PPS salivary gland
neoplasms.
http://dx.doi.org/10.1016/j.ijid.2014.03.1134
Type: Poster Presentation
Final Abstract Number: 58.030
Session: Bacterial Infections
Date: Saturday, April 5, 2014
Time: 12:45-14:15
Room: Ballroom
Studies on bacterial agents of surgical site
infection in Osogbo, South Western Nigeria
M.A. Bisi-Johnson1, O.A. Olowe2
1 Obafemi Awolowo University, Ile-Ife, Nigeria
2 Ladoke Akintola University of Technology, Osogbo,
Nigeria
Background: Surgical site infection is one of the most frequent
types of nosocomial infections in developing countries. The infec-
tion follows interference with the skin barrier, and is associated
with the intensity of bacterial contamination of the wound at
surgery or later in wards during wound care and has been difﬁcult
to manage due to bacterial resistance. The study aim was to iso-
late and identify bacterial agents from patients with postoperative
surgical site infections and assess the antimicrobial susceptibility
patterns of the isolates.
Methods & Materials: A cross sectional study was conducted
at the Ladoke Akintola University Teaching Hospital, Osogbo from
January to March 2013. Seventy surgical samples were collected
using sterile cotton tipped swabs. The samples were analyzed
using standard bacteriological media. All the bacterial isolates thus
obtained were characterized and identiﬁed using standard micro-
biological and biochemical tests, and assessed for sensitivity to
antibiotic of frequent use in the study area.
Results: A total of 70 bacterial pathogens were recovered
from all specimens, 60 samples yielded bacterial growth (51 sam-
ples had pure growth and 9 had mixed growth) while 10 of the
samples showed no bacterial growth.Staphylococcus aureus was
the predominant bacteria18(25.7%) followed by Klebsiella aero-
genes 17(24.3%), Escherichia coli 11(15.7%), Pseudomonas aeruginosa
10(14.3%), coagulase negative staphylococci 9(12.9%), and Proteus
species 5(7.14%). Gram negative rods were deemed highly resis-
tant to most of the antibiotics tested. Of the isolates, 41 (95%), 38
(88.4%), 37 (86.1%), 36 (83.7%), 36 (83.7%), 35 (81.4%) 34 (79.1%),
34 (79.1%) and 31 (72.1%) were found to be resistant to aug-
mentin, amoxycillin, streptomycin, chloranphenicol, peﬂoxacin,
tarivid, gentamycin, septrin, sparﬂoxacin in their respective order.
S. aureus demonstrated high level resistance to cotrimoxazole,
oﬂoxacin, amoxicillin, peﬂoxacin, streptomycin, zinnacef and cef-
triazone. However, ciproﬂoxacin, erythromycin, chloramphenicol
and gentamycin were found to be effective against the S. aureus
isolates.
Conclusion: To keep resistance level to the barest minimum,
it is imperative that all professionals should take an active role in
infection control within their organization. More resources should
beprovided toencouragegoodantibiotic practice andgoodhygiene
in the hospital.
http://dx.doi.org/10.1016/j.ijid.2014.03.1135


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Studies on bacterial agents of surgical site infection in Osogbo, South Western Nigeria

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