Abeliovich, Asa

Angulo, Sergio

Aubry, Laetitia

Chau, Lily

Doege, Claudia

Fujita, Ryousuke

Moreno, Herman

Qiang, Liang

Rhee, David

Rhinn, Herve

Vanti, William B.

Yamashita, Toru

Elsevier - Publisher Connector 

RetractionRetraction Notice to:
Directed Conversion of Alzheimer’s
Disease Patient Skin Fibroblasts
into Functional Neurons
Liang Qiang, Ryousuke Fujita, Toru Yamashita, Sergio Angulo, Herve Rhinn, David Rhee, Claudia Doege, Lily Chau,
Laetitia Aubry, William B. Vanti, Herman Moreno, and Asa Abeliovich*
*Correspondence: aa900@columbia.edu
http://dx.doi.org/10.1016/j.cell.2014.03.002
(Cell 146, 359–371; August 5, 2011)
In this paper, we described the directed conversion of skin fibroblasts from unaffected individuals or familial Alzheimer’s disease
patients into human induced neuronal cells. We also presented molecular analyses of Alzheimer’s-associated markers in these cells.
Dr. Ryousuke Fujita, who was specifically and only responsible for the molecular analyses of Alzheimer’s-associated pathology, has
acknowledged inappropriately manipulating image panels and data points, as well as misrepresenting the number of repeats
performed, in the experiments presented in Figures 6 and 7 of the paper (and corresponding Figures S5 and S6). We are in the
process of repeating these analyses. Given these issues, we believe that themost appropriate course of action is to retract the paper.
We deeply regret this circumstance and apologize to the community.514 Cell 157, 514, April 10, 2014 ª2014 Elsevier Inc.


Retraction Notice to: Directed Conversion of Alzheimer’s Disease Patient Skin Fibroblasts into Functional Neurons 

file:///data/remote/core/dit/data/elsevier/pdf/7ac/aHR0cDovL2FwaS5lbHNldmllci5jb20vY29udGVudC9hcnRpY2xlL3BpaS9zMDA5Mjg2NzQxNDAwMjkxOA==.pdf

Retraction Notice to: Directed Conversion of Alzheimer’s Disease Patient Skin Fibroblasts into Functional Neurons

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