Studies Directed Towards the Synthesis of Protomycinaolide IV

Abstract

Tricarbonyl(diene )iron complexes have been known for over 65 years but have only recently received attention concerning their use in organic synthesis. Several research groups have further shown that acyclic butadiene-iron complexes can be used in asymmetric organic syntheses as well. Furthermore, transition metal dienone complexes are beginning to receive more attention in regards to their use in organic synthesis. However, there appears to be a lack of information on the use of enolates derived from tricarbonyl- (dienone)iron complexes. Therefore, formation of a stabilized tricarbonyl(dienone)iron enolate complex and whether such a species will react with various electrophiles in a stereospecific manner needs to be addressed