Dewi Sartika

ETD - Unsyiah Central Library

ELECTRONIC THESIS AND DISSERTATION UNSYIAHTITLEPENGARUH SALEP EKSTRAK JAMBU BIJI (PSIDIUMN GUAJAVA) TERHADAP PENYEMBUHAN LUKA SKIN LOSSPADA TIKUS PUTIH (RATTUS NORVEGICUS)ABSTRACTABSTRAKWound healing is a complex physiological process in restoring continuity and structure of the tissue due to various mechanisms ofinjury. Many factors that can inhibit wound healing that comes from within and outside the body. Red guava (Psidium guajava) is afruit that contains vitamin C. This study aims to find out the effectiveness of extract ointment the Red Guava loss of skin woundhealing in the rat (Hundred norvegicus) to subcutaneous wound made with a diameter of 1 cm on the backs of mice with ananesthetic injection. These research methodology uses a laboratory experimental (posttest with control group) CompletelyRandomized Design (CRD) of 16 rats aged 3-4 months with average body weight 150-200 grams. Samples were divided 4 groupswith 4 subjects of each group: the group I (control) were given vaseline white (placebo), group II, III and IV are given Guavaextract ointment each with a concentration of 25%, 50%, and 75%. Treatment is as much as 2 times daily at 08.00 and 18.00 hrs.Wound healing observed in the macroscopic everyday. The results showed a mean wound healing in K0, K1, K2, and K3: 13.0 Â±0.00; 9.50 Â± 1.00; 8.25 Â± 0.95; 7.50 Â± 0.57 days. From the data obtained showed guava extract ointment with a concentrationof 75% is very influential on wound healing in mice. Research conclusions are ointments Guava extract having a concentration of75%  more efficacy accelerates loss skin  wound healing in mice.Keywords: Guava Extract Ointment, skin loss injuries, wound healing

PENGARUH SALEP EKSTRAK JAMBU BIJI (PSIDIUMN GUAJAVA) TERHADAP PENYEMBUHAN LUKA SKIN LOSS PADA TIKUS PUTIH (RATTUS NORVEGICUS)

Abstract

Similar works

Full text

Available Versions

ETD - Unsyiah Central Library

uilis.unsyiah.ac.id