In the paper by Astrid Naranjo et al, “Immune-Enhancing Formulas for Patients With Cancer Undergoing Esophagectomy: Systematic Review Protocol” (JMIR Res Protoc 2017;6(11):e214), mistakes were made when listing the authors’ degrees. Laisa Teleni’s highest qualification was incorrectly listed as PhD. The correct degrees for Laisa Teleni are “BBiomedSci (Hon), MND”. Elisabeth Isenring’s degrees were incorrectly listed as “BHSc (Nut &amp; Diet, Hons 1, GradCertHighEd)”. The correct degrees for Elisabeth Isenring are “BHSc (Nut &amp; Diet, Hons 1), PhD”. The affiliations of the authors have not been changed. The corrected article will appear in the online version of the paper on the JMIR website on April 27, 2018, together with the publication of this correction notice. Because this was made after submission to PubMed, Pubmed Central, and other full-text repositories, the corrected article also has been re-submitted to those repositories.</p

Isenring, Elizabeth

Naranjo, Astrid

Teleni, Laisa

JMIR Research Protocols

English

Bond University Research Portal

Bond UniversityResearch RepositoryMetadata correction: Immune-enhancing formulas for patients with cancer undergoingesophagectomy: Systematic review protocol (Journal of Medical Internet Research (2017)6:11 (e214) DOI: 10.2196/resprot.7688)Naranjo, Astrid; Isenring, Elizabeth; Teleni, LaisaPublished in:Journal of Medical Internet ResearchDOI:10.2196/resprot.9615Published: 01/04/2018Document Version:Publisher's PDF, also known as Version of recordLink to publication in Bond University research repository.Recommended citation(APA):Naranjo, A., Isenring, E., & Teleni, L. (2018). Metadata correction: Immune-enhancing formulas for patients withcancer undergoing esophagectomy: Systematic review protocol (Journal of Medical Internet Research (2017)6:11 (e214) DOI: 10.2196/resprot.7688). Journal of Medical Internet Research, 20(4), [e61].https://doi.org/10.2196/resprot.9615General rightsCopyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright ownersand it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.For more information, or if you believe that this document breaches copyright, please contact the Bond University research repositorycoordinator.Download date: 09 Oct 2020Corrigenda and AddendaMetadata Correction: Immune-Enhancing Formulas for PatientsWith Cancer Undergoing Esophagectomy: Systematic ReviewProtocolAstrid Naranjo, BNutr & Diet (Hons), MNutr & Diet Prac; Elizabeth Isenring, BHSc (Nut & Diet, Hons 1), PhD;Laisa Teleni, BBiomedSci (Hon), MNDFaculty of Health Sciences and Medicine, Bond University, Gold Coast, AustraliaCorresponding Author:Astrid Naranjo, BNutr & Diet (Hons), MNutr & Diet PracFaculty of Health Sciences and MedicineBond University14 University DriveRobina, QLDGold Coast, 4226AustraliaPhone: 61 426844919Fax: 61 75595352Email: a.naranjomartinez@student.bond.edu.auRelated Article:Correction of: http://www.researchprotocols.org/2017/11/e214/(JMIR Res Protoc 2018;7(4):e61)  doi: 10.2196/resprot.9615In the paper by Astrid Naranjo et al, “Immune-EnhancingFormulas for Patients With Cancer Undergoing Esophagectomy:Systematic Review Protocol” (JMIR Res Protoc2017;6(11):e214), mistakes were made when listing the authors’degrees. Laisa Teleni’s highest qualification was incorrectlylisted as PhD. The correct degrees for Laisa Teleni are“BBiomedSci (Hon), MND”. Elisabeth Isenring’s degrees wereincorrectly listed as “BHSc (Nut & Diet, Hons 1,GradCertHighEd)”. The correct degrees for Elisabeth Isenringare “BHSc (Nut & Diet, Hons 1), PhD”. The affiliations of theauthors have not been changed.The corrected article will appear in the online version of thepaper on the JMIR website on April 27, 2018, together with thepublication of this correction notice. Because this was madeafter submission to PubMed, Pubmed Central, and other full-textrepositories, the corrected article also has been re-submitted tothose repositories.Edited by G Eysenbach; this is a non–peer-reviewed article. Submitted 10.12.17; accepted 15.12.17; published 27.04.18.Please cite as:Naranjo A, Isenring E, Teleni LMetadata Correction: Immune-Enhancing Formulas for Patients With Cancer Undergoing Esophagectomy: Systematic ReviewProtocolJMIR Res Protoc 2018;7(4):e61URL: http://www.researchprotocols.org/2018/4/e61/doi: 10.2196/resprot.9615PMID: 30578224©Astrid Naranjo, Elisabeth Isenring, Laisa Teleni. Originally published in JMIR Research Protocols(http://www.researchprotocols.org), 27.04.2018. This is an open-access article distributed under the terms of the Creative CommonsAttribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproductionin any medium, provided the original work, first published in JMIR Research Protocols, is properly cited. The complete bibliographicJMIR Res Protoc 2018 | vol. 7 | iss. 4 | e61 | p. 1http://www.researchprotocols.org/2018/4/e61/(page number not for citation purposes)Naranjo et alJMIR RESEARCH PROTOCOLSXSL•FORenderXinformation, a link to the original publication on http://www.researchprotocols.org, as well as this copyright and license informationmust be included.JMIR Res Protoc 2018 | vol. 7 | iss. 4 | e61 | p. 2http://www.researchprotocols.org/2018/4/e61/(page number not for citation purposes)Naranjo et alJMIR RESEARCH PROTOCOLSXSL•FORenderX

Metadata correction: Immune-enhancing formulas for patients with cancer undergoing esophagectomy: Systematic review protocol (Journal of Medical Internet Research (2017) 6:11 (e214) DOI: 10.2196/resprot.7688)

Astrid Naranjo

Elizabeth Isenring

Laisa Teleni

Crossref

Metadata Correction: Immune-Enhancing Formulas for Patients With Cancer Undergoing Esophagectomy: Systematic Review Protocol

BACKGROUND: Adult patients with an esophageal cancer can potentially be compromised with postoperative leaks or fistulae if patients' nutritional status is in a vulnerable stage. Currently in Australia, there is a growing need for clinicians to know whether use of immune-enhancing formulas (IEFs) containing Arg, omega-3, and RNA are a cost-effective approach compared with isonitrogenous-isocaloric formulas to reduce postoperative infectious complications in esophagectomy patients. Since IEFs may carry higher costs, this has led to inconsistencies in practice among clinicians and hospitals.OBJECTIVE: Our aim is to compile and present the most up-to-date nutrition evidence available regarding the provision of IEFs containing Arg, omega-3, and RNA to help clinicians develop an evidence-based nutrition care plan; identify available evidence of whether an esophagectomy patient should receive IEF; determine the cost-effectiveness and safety of such nutrition; and determine appropriate administration quantity and timing (pre-, peri-, or postesophagectomy).METHODS: This review will include RCTs involving the use of IEFs enriched with Arg, omega-3 polyunsaturated fatty acids, and RNA in the pre-, peri-, or postoperative period (for at least 5-7 days) given orally or via enteral feeding tube, in adult cancer patients undergoing esophageal resection. Lower gastrointestinal, gastric, or head cancer surgery with parenteral nutrition or non-IEF or use of isolated immunonutrient (Arg vs omega-3 vs RNA) will be excluded. Primary outcome comprises postoperative infectious complications. Secondary outcomes (pre/postoperatively) consist of cost-effectiveness, length of stay, survival/mortality, quality of life, nutritional status, percentage of weight loss, and biochemical changes. The risk of bias will be independently assessed by the reviewers, using a domain-based evaluation tool. Blinding will be assessed for subjective and objective outcome measures. Publication bias will be visually assessed by funnel plots. A meta-analysis will be generated by the Review Manager 5.3 software and represented in forest plots.RESULTS: The first results are expected in 2018. Outlining the protocol will ensure transparency for the completed review.CONCLUSIONS: This protocol for a systematic review and meta-analysis will enable a comprehensive appraisal of the literature to help determine whether overall institutional savings are associated with this approach. Findings will form a knowledge base relevant to stakeholders across the health system and researchers who are involved in decision making on evidence-based nutrition care plan pathways for patients undergoing esophagectomy, as well as the use of IEF, timing, and administration quantity.TRIAL REGISTRATION: PROSPERO Registration Number: CRD42017056908; http://www.crd.york.ac.uk/PROSPERO/ display_record.asp? ID=CRD42017056908 (Archived by WebCite at http://www.webcitation.org/6rLyeqaD6).See also: Correction to this article</p