SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Borras Senabre, Manuel Enrique

Gupta, Ranju

Jindal, Dharam Paul

Leclercq, Guy

Legros, Nicole

563-5713-Methoxy-17-aza-D-homo-1,3,5(10)-estratrienc-16, 17a-dione 3, 16, 17a-dioxo-17-aza-D-homo-1,3,5(10)-estratrien-3-yl
acctate 12 and a series of related
compounds have been synthesised from 3-methoxy-16-oximino- 1,3,5 (10)-estrairian-17-

one 1 and 3-hydroxy-16-oximino-
1,3,5 (10)-estnttrien-17-one 2, respectively.
The compounds 3 (DPJ-280), 14 (DPJ-369),
17 (DPJ-370), <b style="mso-bidi-font-weight:
normal">18 (DPJ-354), 19
(DPJ-320), 21 (DPJ- 321 ), 22
(DPJ-374) and (DPJ-284) have been evaluated for their

estrogenic/antiestrogenic effects and the
compounds 3-7<b style="mso-bidi-font-weight:
normal">,8,9,10,12,15,16,18,20,21,23 and <b style="mso-bidi-font-weight:
normal">24 have been screened for antineoplastic activity at NCI, Bethesda.</span

Synthesis and biological activity of some D-ring modified estrone derivatives

Abstract

Similar works

Full text

Available Versions

NOPR

DI-fusion