Fujii, Kenichi

Fukunaga, Masashi

Imanaka, Takahiro

Masuyama, Tohru

Miki, Kojiro

Ohyanagi, Mitsumasa

Tamaru, Hiroto

Elsevier - Publisher Connector 

TCT@ACC-i2: The Interventional Learning Pathway
A1833
JACC April 1, 2014
Volume 63, Issue 12
the influence of iliAc Artery occlusion on centrAl blooD Pressure AnD AugMentAtion 
inDex At the AscenDing AortA
Poster Contributions
Hall C
Sunday, March 30, 2014, 9:45 a.m.-10:30 a.m.
Session Title: Carotid and Endovascular Intervention
Abstract Category: 37. TCT@ACC-i2: Carotid and Endovascular Intervention
Presentation Number: 2106-310
Authors: Kojiro Miki, Kenichi Fujii, Masashi Fukunaga, Hiroto Tamaru, Takahiro Imanaka, Mitsumasa Ohyanagi, Tohru Masuyama, Hyogo College of 
Medicine, Nishinomiya, Japan
background: Central blood pressure and augmentation index (AI) are surrogate indicators of systolic arterial load to left ventricle, which results 
in deteriorated left ventricular relaxation. We hypothesized that vessel occlusion of the iliac artery has negative influence on central hemodynamic 
parameters.
Methods: Thirteen patients who underwent endovascular therapy (EVT) for isolated iliac artery lesions were enrolled. The ascending aortic pressure 
waves were obtained using a 5Fr catheter immediately after successful EVT with stent implantation and during balloon occlusion of the iliac artery. 
From the pressure waveforms at the ascending aorta, AI and central hemodynamic parameters were calculated. AI was calculated as augmented 
pressure divided by central pulse pressure (Figure).
results: Central systolic pressure and AI at the ascending aorta measured immediately after EVT were significantly lower than those measured 
during balloon occlusion of the iliac artery (169.0±27.5 vs. 178.4±28.1 mmHg, p<0.01, and 0.32±0.16 vs. 0.35±0.17, p=0.02, respectively). In 
5 patients, who had chronic total occlusion of the iliac artery, pre- and post-procedural AIs were measured, and it showed that post-procedural AI 
decreased from 0.39±0.11 to 0.30±0.06.
conclusion: Temporal vessel occlusion of the iliac artery has negative influence on central hemodynamic parameters. EVT for totally occluded iliac 
artery lesions may improve left ventricular relaxation for patients with peripheral artery disease.
 


THE INFLUENCE OF ILIAC ARTERY OCCLUSION ON CENTRAL BLOOD PRESSURE AND AUGMENTATION INDEX AT THE ASCENDING AORTA 

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THE INFLUENCE OF ILIAC ARTERY OCCLUSION ON CENTRAL BLOOD PRESSURE AND AUGMENTATION INDEX AT THE ASCENDING AORTA

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