E Iglesias

J Antón-López

J Carbonell

J Sanchez

MI Gonzalez

R Bou

S Ricart

T Salman-Monte

V Torrente-Segarra

Pediatric Rheumatology

PubMed

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POSTER PRESENTATION Open Access
PReS-FINAL-2309: Juvenile systemic lupus
erythematosus: a case series depiction in an
urban community and a comparison to an
adult case series
V Torrente-Segarra1*, E Iglesias1, MI Gonzalez1, J Sanchez1, S Ricart1, R Bou1, T Salman-Monte2, J Carbonell2,
J Antón-López1
From 20th Pediatric Rheumatology European Society (PReS) Congress
Ljubljana, Slovenia. 25-29 September 2013
Introduction
Clinical features comparison between adut and pediatric
SLE patients.
Objectives
to describe clinical and serological features of juvenile
Systemic Lupus Erythematosus (jSLE) patients; to com-
pare the main differences between jSLE characteristics
and adult SLE (aSLE).
Methods
we detected all our jSLE patients from our database. We
collected sociodemographic data and both clinical and
serological variables from our jSLE patients’ charts at Hos-
pital Sant Joan de Déu, Esplugues (Catalunya, Spain). We
defined the following variables: cutaneous disease (as pre-
sence of discoid lupus, photosensitivity, and/or malar
rash), joint disease (arthritis), hematological disease
(anemia, leucopenia, and/or plaquetopenia), renal disease
(>0.5 g/d proteinuria and, if available, histological WHO
class), neurolupus (psychosis and/or convulsions). We
collected the following data: age at onset, time disease
evolution, and gender. In regarding to serological markers:
DNAds positivity through follow-up was recorded. We
also collected information from a well-recognised aSLE
cohort of 124 patients in the same Mediterranean urban
area. We analysed all data in order to depict the type of
clinical and serological features for each group of patients.
Results
we assessed charts from 42 jSLE (n = 42), and compared
to aSLE (n = 124). 90% of the jSLE patients were female,
compared to a 95% of the aSLE cohort. Age at onset was
12.1 years in jSLE. In the jSLE group of patients: 81% had
had cutaneous disease, 62% haematological disorder, 44%
arthritis, 40% nephropathy (60% class IV, 20% class III,
10% class II and 10% class V), and 14% convulsions. In the
aSLE cohort: 80% had cutaneous disease, 54% haematolo-
gical disorder, 29% arthritis, 14% nephropathy and 3.2%
neuro-lupus. DNAds positivity was 68% in jSLE and 54.8%
in aSLE.
Conclusion
jSLE and aSLE are slightly different in our Mediterranean
region. Most of cases were women and main features were
similar in both groups. Pediatric patients had more
frequently nephropathy (most of them class IV-WHO),
and DNAds positivity. Further follow-up, in which are
already involved, is needed to assess the outcome of our
jSLE.
Disclosure of interest
None declared.
Authors’ details
1Pediatric Rheumatology, Hospital Sant Joan Deu, Esplugues Llobregat,
Spain. 2Rheumatology, Hospital del Mar, Barcelona, Spain.
1Pediatric Rheumatology, Hospital Sant Joan Deu, Esplugues Llobregat, Spain
Full list of author information is available at the end of the article
Torrente-Segarra et al. Pediatric Rheumatology 2013, 11(Suppl 2):P299
http://www.ped-rheum.com/content/11/S2/P299
© 2013 Torrente-Segarra et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative
Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and
reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver
(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Published: 5 December 2013
doi:10.1186/1546-0096-11-S2-P299
Cite this article as: Torrente-Segarra et al.: PReS-FINAL-2309: Juvenile
systemic lupus erythematosus: a case series depiction in an urban
community and a comparison to an adult case series. Pediatric
Rheumatology 2013 11(Suppl 2):P299.
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Torrente-Segarra et al. Pediatric Rheumatology 2013, 11(Suppl 2):P299
http://www.ped-rheum.com/content/11/S2/P299
Page 2 of 2


PReS-FINAL-2309: Juvenile systemic lupus erythematosus: a case series depiction in an urban community and a comparison to an adult case series

http://dx.doi.org/10.1186/1546-0096-11-S2-P299

PReS-FINAL-2309: Juvenile systemic lupus erythematosus: a case series depiction in an urban community and a comparison to an adult case series

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