Experimental results for the determination of internalization rates for IGF1-IGF1R, IGF2-IGF1R, IGF2-IGF2R. (PDF 162Â kb

Dan Tian

Isaiah Mitchell

Pamela K. Kreeger

Analysis of the TCGA data for IGF2R. (PDF 184Â kb

Dan Tian (697937)

Isaiah Mitchell (3494420)

Pamela Kreeger (3494423)

The Francis Crick Institute

Additional file 4: of Quantitative analysis of insulin-like growth factor 2 receptor and insulin-like growth factor binding proteins to identify control mechanisms for insulin-like growth factor 1 receptor phosphorylation

Experimental validation of the impact of IGF1R and IR inhibition on IGF2-induced cell proliferation, demonstrating that IGF2-induced proliferation was dependent on IGF1R kinase activity and not IR kinase activity. (PDF 104Â kb

Additional file 6: of Quantitative analysis of insulin-like growth factor 2 receptor and insulin-like growth factor binding proteins to identify control mechanisms for insulin-like growth factor 1 receptor phosphorylation

Additional file 2: of Quantitative analysis of insulin-like growth factor 2 receptor and insulin-like growth factor binding proteins to identify control mechanisms for insulin-like growth factor 1 receptor phosphorylation

Springer - Publisher Connector

Quantitative analysis of insulin-like growth factor 2 receptor and insulin-like growth factor binding proteins to identify control mechanisms for insulin-like growth factor 1 receptor phosphorylation

Detailed methods including the full set of differential equations and assumptions used in the model, experimental methods for determination of several rates and initial conditions, experimental methods for validation of the IGF2R knockdown and overexpression, and tables of both experimentally-determined and model-fitted rates and initial conditions. (DOCX 80Â kb

Additional file 1: of Quantitative analysis of insulin-like growth factor 2 receptor and insulin-like growth factor binding proteins to identify control mechanisms for insulin-like growth factor 1 receptor phosphorylation

https://figshare.com/articles/Additional_file_1_of_Quantitative_analysis_of_insulin-like_growth_factor_2_receptor_and_insulin-like_growth_factor_binding_proteins_to_identify_control_mechanisms_for_insulin-like_growth_factor_1_receptor_phosphorylation/4391945

Quantitative analysis of insulin-like growth factor 2 receptor and insulin-like growth factor binding proteins to identify control mechanisms for insulin-like growth factor 1 receptor phosphorylation

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The Francis Crick Institute

The Francis Crick Institute

The Francis Crick Institute

Springer - Publisher Connector

The Francis Crick Institute