[EN] Objective: To analyze the relationship between dietary glycemic index (GI) and retinal microvasculature in adults.
Methods: This was a cross-sectional study of 300 subjects from the EVIDENT II study. Dietary GI was calculated
using a validated, semi-quantitative food frequency questionnaire. Retinal photographs were digitized, temporal
vessels were measured in an area 0.5–1 disc diameter from the optic disc and arteriolar-venular index (AVI) was
estimated with semi-automated software.
Results: AVI showed a significant difference between the tertiles of GI, after adjusting for potential confounders.
The lowest AVI values were observed among subjects in the highest tertile of GI, whereas the greatest were found
among those in the lowest tertile (estimated marginal mean of 0.738 vs. 0.768, p = 0.014).
Conclusions: In adults, high dietary GI implies lowering AVI values regardless of age, gender and other
confounding variables.
Trial registration: Clinical Trials.gov Identifier: NCT02016014. Registered 9 December 2013