Biswarup Purkayastha

Chakrabarti Amitabha

Lokesh Kukatla

Sanjib K Pattari

Journal of Cardiothoracic Surgery

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MEETING ABSTRACT Open Access
Primary Pericardial Angiosarcoma: A Case Report
and Review of Literature
Chakrabarti Amitabha1,2, Biswarup Purkayastha1*, Lokesh Kukatla3, Sanjib K Pattari4
From World Society of Cardiothoracic Surgeons 25th Anniversary Congress, Edinburgh
Edinburgh, UK. 19-22 September 2015
Background/Introduction
58-year-old diabetic, ex-smoker with shortness of breath,
recurrent pericardial effusion with impending cardiac
tamponade was diagnosed with a pericardial mass on
computed tomography, underwent surgical resection
(partial pericardiectomy). Histopathology and immuno-
histochemistry clinched the diagnosis of Pericardial
Angiosarcoma. He refused further treatment.
Aims/Objectives
To augment our understanding of Cardiac and Pericar-
dial Angiosarcoma and formulate a proper investigation
workup plan including imaging modality of choice and
multi-modality management plan.
Method
PubMed and Google were searched for primary refer-
ences using the terms “Cardiac Angiosarcoma” “Pericar-
dial Angiosarcoma” “Treatment of Angiosarcoma” and
“Newer Therapies in Angiosarcoma”. The Case Reports,
Case Series and Review articles obtained were thor-
oughly reviewed.
Results
Shortness of Breath remains the most common symp-
tom with Trans Thoracic Echocardiography as Investiga-
tion of Choice, but Computed Tomography(CT) and
Magnetic Resonance (MRI) being of more yield.
The disease shows a distinct male preponderance with
64.2% being male. Mean age of presentation being 44.15 ±
19.65 years. Surgical Resection - alone or in conjunction,
was done in 85.7% (reviewed in Table 1), 1 patient was
managed conservatively, 1 patient refused treatment. Novel
treatments have shown promise demanding further research
Discussion/Conclusion
Cardiac and Pericardial angiosarcoma are rare, aggres-
sive neoplasm often presenting late with loco regional
metastasis, thus jeopardising operability and prognosis.
Echocardiography is used most commonly, in addition
HRCT(High Resolution CT) and MRI have been used
for better cross sectional imaging. And 18 FDG PET-CT
(Positron Emission Tomography - Computed Tomogra-
phy) apart from being an useful adjunct, possibly would
become the imaging modality of choice in coming dec-
ades. Surgical Resection - alone or in conjunction,
remains the most commonly used treatment modality.
Novel treatments with monoclonal antibodies and che-
motherapeutic agents have shown excellent results and
merit further research.
Consent
Written informed consent was obtained from the patient
for publication of this abstract and any accompanying
images. A copy of the written consent is available for
review by the Editor of this journal.
Authors’ details
1Department of Cardio Thoracic and Vascular Surgery, NH Rabindranath
Tagore International Institute of Cardiac Sciences, Kolkata, India. 2Department
of Cardio Thoracic and Vascular Surgery, KPC Medical College, Kolkata, India.
3Department of Radio Diagnosis, NH Rabindranath Tagore International
Institute of Cardiac Sciences, Kolkata, India. 4Department of Pathology, NH
Rabindranath Tagore International Institute of Cardiac Sciences, Kolkata,
India.
Published: 16 December 2015
doi:10.1186/1749-8090-10-S1-A36
Cite this article as: Amitabha et al.: Primary Pericardial Angiosarcoma: A
Case Report and Review of Literature. Journal of Cardiothoracic Surgery
2015 10(Suppl 1):A36.
1Department of Cardio Thoracic and Vascular Surgery, NH Rabindranath
Tagore International Institute of Cardiac Sciences, Kolkata, India
Full list of author information is available at the end of the article
Amitabha et al. Journal of Cardiothoracic Surgery 2015, 10(Suppl 1):A36
http://www.cardiothoracicsurgery.org/content/10/S1/A36
© 2015 Amitabha et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://
creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the
original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/
zero/1.0/) applies to the data made available in this article, unless otherwise stated.


Primary Pericardial Angiosarcoma: A Case Report and Review of Literature

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Primary Pericardial Angiosarcoma: A Case Report and Review of Literature

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