A study on selected EU cities of the Danube macro-region concludes that energy production/industry, agriculture, residential heating and transportation are the main pollution sources. Long –range transport of pollutants from within and outside EU-28 has considerable impacts in certain cities while in others local emissions are the key to reduce urban pollution. Measures to be adopted at different policy levels to address the identified issues are analysed and the cross-policy implications are discussed.JRC.C.5-Air and Climat