The aim of our study was to determine whether such skin repair ability of liposomes would also apply to damage caused by low-frequency ultrasound. The latter is being investigated in our laboratories for skin vaccination. Thus, the effects of US and liposomes on the in vitro skin permeation of a model antigen (bovine serum albumin (BSA)) and the in vivo trans-epidermal water loss (TEWL - an indicator of skin barrier properties) were determined