Correlation of bicarbonate values measured with direct enzymatic method and blood gas analysis devices

Abstract

Ankarali, Handan Camdeviren/0000-0002-3613-0523WOS: 000300974400013Introduction: In this study, we investigated to whether there is a relationship between bicarbonate levels simultaneously measured with the mathematical calculation of blood gas analysis device derived pH and pCO(2) and direct enzymatic method. Materials and methods: Arterial blood samples were taken from 90 patients hospitalized in the intensive care unit. Bicarbonate level was simultaneously measured in the ABL 800 blood gas analyzer with the method of mathematical calculation from the pH and pCO2 and in the Roche Diagnostics Cobas c501 with the enzymatic method. The results were compared. Results: Pearson correlation coefficient between the two measurements was r=0.944 showing a significant positive relationship. Also value of the ICC calculation which was 0.963 showed that there was a significant agreement between the two measurement methods (p=0.0001). None of the 90 values were not out of the agreement limits, as shown in Bland-Altman graphic. Conclusion: The present study showed that bicarbonate measurements with the blood gas analyzers which give quick results are reliable and acceptable when compared with the results of the direct enzymatic method. Conflict of interests: Authors have no conflict of interest