Currently, there is no doubt surrounding a theory that the cardiotropic e ects of sex hormones can be due to their direct e ect on the cardiovascular system. In recent years, interest in the study of steroid glycosides has increased. We studied the e ects of furostanol glycosides (protodioscin and deltozid) from the cell culture of the Dioscorea deltoidea (laboratory code DM-05) on the physiological and biochemical parameters of vascular endothelial function in hypoestrogen-induced endothelial dysfunction after bilateral ovariectom