Barbon, Francesca

Lazzarotto, Francesca

Muraro, Antonella

Toniolo, Alice

English

PubMed

Barbon Francesca

Lazzarotto Francesca

Toniolo Alice

Muraro Antonella

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Clinical and Translational Allergy

Late resolution of cow’s milk and egg allergy: experience at a third level centre

Francesca Barbon

Francesca Lazzarotto

Alice Toniolo

Antonella Muraro

Springer - Publisher Connector

POSTER PRESENTATION Open Access
Late resolution of cow’s milk and egg allergy:
experience at a third level centre
Francesca Barbon*, Francesca Lazzarotto, Alice Toniolo, Antonella Muraro
From Food Allergy and Anaphylaxis Meeting 2011
Venice, Italy. 17-19 February 2011
Background
Cow’s milk allergy affects about 2-3 % of general popu-
lation; the prevalence of egg allergy is 1-2% among
childhood. According to the literature the development
of tolerance for cow’s milk and for egg is reached in
early childhood, in the majority of case. In addiction it
is reported that over six years of age there is a signifi-
cant decrease in the resolution rate both for cow’s milk
and egg allergy.
Objective
The aim of this study is to define the rate of allergy
resolution over time in a selected population of cow’s
milk and egg allergy patients.
Methods
We conducted a retrospective study on 110 patients, 42
with cow’s milk and 68 with egg allergy, which attend
the Food Allergy Centre, Padua, Veneto. All the patients
studied were between 5 and 15 years and they had not
yet developed tolerance to egg or milk. The lack of tol-
erance was confirmed by an oral food challenge (OFC).
A descriptive analysis was conducted on the collected
data.
Result
The development of tolerance was reached in 66,7% (28)
patients with cow’s milk allergy, in particular 57.1% (16)
from 6 to 7 years old, 17.8% (5) from 8 to 9 years old,
7.2% (2) from 10 to 11 years old, 14.3% (4) from 12 to
13 and 3.6% (1) from 14 to 15. The total percentage of
patients who achieved tolerance to egg was 67.6%. The
distribution among the different groups of age is as fol-
low: 58.7% (27) from 6 to 7 years old, 13.1% (6) from 8
to 9 years old, 15.2% (7) from 10 to 11 years old, 6.5%
(3) from 12 to 13 and 6.5% (3) from 14 to 15.
Conclusion
Our data show that achieving of tolerance is still possi-
ble for both cow’s milk and egg at ages older than six
years. The rates of resolution for both cow’s milk and
egg allergy between different rising age groups are simi-
lar. In spite of several limitations for a non homoge-
neous and non proportional distribution of patients
between the different ages, the results underline the
importance of monitoring the older children with OFC
during years at, at least, yearly intervals as some of these
children can still outgrow their food allergy.
Published: 12 August 2011
doi:10.1186/2045-7022-1-S1-P31
Cite this article as: Barbon et al.: Late resolution of cow’s milk and egg
allergy: experience at a third level centre. Clinical and Translational Allergy
2011 1(Suppl 1):P31.
Submit your next manuscript to BioMed Central
and take full advantage of: 
• Convenient online submission
• Thorough peer review
• No space constraints or color figure charges
• Immediate publication on acceptance
• Inclusion in PubMed, CAS, Scopus and Google Scholar
• Research which is freely available for redistribution
Submit your manuscript at 
www.biomedcentral.com/submitFood Allergy Centre, Padua University Hospital, Dept. of Pediatrics, Padova,
Italy
Barbon et al. Clinical and Translational Allergy 2011, 1(Suppl 1):P31
http://www.ctajournal.com/content/1/S1/P31
© 2011 Barbon et al; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons
Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in
any medium, provided the original work is properly cited.


Crossref

POSTER PRESENTATION Open AccessLate resolution of cow’s milk and egg allergy:experience at a third level centreFrancesca Barbon*, Francesca Lazzarotto, Alice Toniolo, Antonella MuraroFrom Food Allergy and Anaphylaxis Meeting 2011Venice, Italy. 17-19 February 2011BackgroundCow’s milk allergy affects about 2-3 % of general popu-lation; the prevalence of egg allergy is 1-2% amongchildhood. According to the literature the developmentof tolerance for cow’s milk and for egg is reached inearly childhood, in the majority of case. In addiction itis reported that over six years of age there is a signifi-cant decrease in the resolution rate both for cow’s milkand egg allergy.ObjectiveThe aim of this study is to define the rate of allergyresolution over time in a selected population of cow’smilk and egg allergy patients.MethodsWe conducted a retrospective study on 110 patients, 42with cow’s milk and 68 with egg allergy, which attendthe Food Allergy Centre, Padua, Veneto. All the patientsstudied were between 5 and 15 years and they had notyet developed tolerance to egg or milk. The lack of tol-erance was confirmed by an oral food challenge (OFC).A descriptive analysis was conducted on the collecteddata.ResultThe development of tolerance was reached in 66,7% (28)patients with cow’s milk allergy, in particular 57.1% (16)from 6 to 7 years old, 17.8% (5) from 8 to 9 years old,7.2% (2) from 10 to 11 years old, 14.3% (4) from 12 to13 and 3.6% (1) from 14 to 15. The total percentage ofpatients who achieved tolerance to egg was 67.6%. Thedistribution among the different groups of age is as fol-low: 58.7% (27) from 6 to 7 years old, 13.1% (6) from 8to 9 years old, 15.2% (7) from 10 to 11 years old, 6.5%(3) from 12 to 13 and 6.5% (3) from 14 to 15.ConclusionOur data show that achieving of tolerance is still possi-ble for both cow’s milk and egg at ages older than sixyears. The rates of resolution for both cow’s milk andegg allergy between different rising age groups are simi-lar. In spite of several limitations for a non homoge-neous and non proportional distribution of patientsbetween the different ages, the results underline theimportance of monitoring the older children with OFCduring years at, at least, yearly intervals as some of thesechildren can still outgrow their food allergy.Published: 12 August 2011doi:10.1186/2045-7022-1-S1-P31Cite this article as: Barbon et al.: Late resolution of cow’s milk and eggallergy: experience at a third level centre. Clinical and Translational Allergy2011 1(Suppl 1):P31.Submit your next manuscript to BioMed Centraland take full advantage of: • Convenient online submission• Thorough peer review• No space constraints or color figure charges• Immediate publication on acceptance• Inclusion in PubMed, CAS, Scopus and Google Scholar• Research which is freely available for redistributionSubmit your manuscript at www.biomedcentral.com/submitFood Allergy Centre, Padua University Hospital, Dept. of Pediatrics, Padova,ItalyBarbon et al. Clinical and Translational Allergy 2011, 1(Suppl 1):P31http://www.ctajournal.com/content/1/S1/P31© 2011 Barbon et al; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative CommonsAttribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction inany medium, provided the original work is properly cited.

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Late resolution of cow’s milk and egg allergy: experience at a third level centre

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