Asano, Masahide

Atsumi, Takashi

Iwakura, Yoichiro

Ohara, Kenji

Ohtaki, Hirokazu

Sato, Atsushi

Shioda, Seiji

Song, Dandan

Tsumuraya, Tomomi

English

PubMed

Atsushi Sato

Hirokazu Ohtaki

Tomomi Tsumuraya

Dandan Song

Kenji Ohara

Masahide Asano

Yoichiro Iwakura

Takashi Atsumi

Seiji Shioda

Springer - Publisher Connector

Interleukin-1 participates in the classical and alternative activation of microglia/macrophages after spinal cord injury

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature

A: Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury. Nat Med

Allan SM: Regulation of interleukin-1 in acute brain injury. Trends Pharmacol Sci

Allavena P: Decoy receptors: a strategy to regulate inflammatory cytokines and chemokines. Trends Immunol

Alternative activation of macrophages. Nat Rev Immunol

Aruga T: Gp91phox (NOX2) in classically activated microglia exacerbates traumatic brain injury.

Ascending sensory, but not other long-tract axons, regenerate into the connective tissue matrix that forms at the site of a spinal cord injury in mice.

Astrocytes initiate inflammation in the injured mouse spinal cord by promoting the entry of neutrophils and inflammatory monocytes in an IL-1 receptor/MyD88-dependent fashion. Brain Behav Immun

Beneficial effect of interleukin-1 receptor antagonist protein on spinal cord injury recovery in the rat. Inflammation .

Cannizzaro LA: Molecular cloning of the interleukin-1 beta converting enzyme. Science

Cerebrovascular inflammation following subarachnoid hemorrhage.

Cheng H: Acid fibroblast growth factor and peripheral nerve grafts regulate Th2 cytokine expression, macrophage activation, polyamine synthesis, and neurotrophin expression in transected rat spinal cords.

Clinical experience using incubated autologous macrophages as a treatment for complete spinal cord injury: phase I study results.

DD: Interleukin-1 alpha and beta genes: linkage on chromosome 2 in the mouse. Immunogenetics

Dittel BN: CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells.

DM: Reversal of proinflammatory responses by ligating the macrophage Fcgamma receptor type I. J Exp Med

Faden AI: Expression of two temporally distinct microgliarelated gene clusters after spinal cord injury. Glia

FO: Alternative activation of macrophages: mechanism and functions. Immunity

GA: Acute rolipram/thalidomide treatment improves tissue sparing and locomotion after experimental spinal cord injury. Exp Neurol

Ghabriel MN: Severity-dependent expression of proinflammatory cytokines in traumatic spinal cord injury in the rat.

H: IL-1beta promotes neurite outgrowth by deactivating RhoA via p38 MAPK pathway. Biochem Biophys Res Commun

H: Interleukin-1 receptor antagonist attenuates the severity of spinal cord ischemic injury in rabbits. J Vasc Surg

Heijnen CJ: IL-1 beta signaling is required for mechanical allodynia induced by nerve injury and for the ensuing reduction in spinal cord neuronal GRK2. Brain Behav Immun

HJ: A new method to isolate microglia from adult mice and culture them for an extended period of time.

Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood. Nat Neurosci

Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats. Nat Med

Interleukin (IL)-1 and IL-6 regulation of neural progenitor cell proliferation with hippocampal injury: differential regulatory pathways in the subgranular zone (SGZ) of the adolescent and mature mouse brain. Brain Behav Immun

Interleukin-1 and neuronal injury: mechanisms, modification, and therapeutic potential. Brain Behav Immun

Interleukin-4 receptor signaling pathways in asthma pathogenesis. Trends Mol Med

JA: Potential antiinflammatory effects of interleukin 4: suppression of human monocyte tumor necrosis factor alpha, interleukin 1, and prostaglandin E2. Proc Natl Acad Sci USA

JA: Role of interleukin-1beta in the control of neuroepithelial proliferation and differentiation of the spinal cord during development. Cytokine

JW: An IL-1 receptor antagonist blocks a morphine-induced attenuation of locomotor recovery after spinal cord injury. Brain Behav Immun

Kogure K: Interleukin-1 as a pathogenetic mediator of ischemic brain damage in rats. Stroke

Local isoform-specific NOS inhibition: a promising approach to promote motor function recovery after nerve injury.

Macrophage activation and polarization. Front Biosci

McAdoo DJ: Regulation of interleukin-1beta by the interleukin-1 receptor antagonist in the glutamate-injured spinal cord: endogenous neuroprotection. Brain Res

Mosser DM: A novel phenotype for an activated macrophage: the type 2 activated macrophage.

NJ: Interleukin-1 and inflammatory neurodegeneration. Biochem Soc Trans

NJ: Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat.

NJ: Role of IL-1alpha and IL-1beta in ischemic brain damage.

Orfanos CE: Alternative versus classical activation of macrophages. Pathobiology

Perez-Pol R: IL-1 receptor antagonist prevents apoptosis and caspase-3 activation after spinal cord injury.

PG: Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord.

Primary murine microglia are resistant to nitric oxide inhibition of indoleamine 2,3-dioxygenase. Brain Behav Immun

Production of mice deficient in genes for interleukin (IL)-1alpha, IL-1beta, IL-1alpha/beta, and IL-1 receptor antagonist shows that IL-1beta is crucial in turpentine-induced fever development and glucocorticoid secretion.

Proinflammatory cytokine synthesis in the injured mouse spinal cord: multiphasic expression pattern and identification of the cell types involved.

Ransohoff RM: Isolation of murine microglial cells for RNA analysis or flow cytometry. Nat Protoc

RP: Cytokine activity contributes to induction of inflammatory cytokine mRNAs in spinal cord following contusion.

S: Alternative activation of macrophages: an immunologic functional perspective. Annu Rev Immunol

Saporta S: Methylprednisolone inhibits production of interleukin1beta and interleukin-6 in the spinal cord following compression injury in rats.

Schwab ME: Effects of pro-inflammatory cytokines in experimental spinal cord injury. Brain Res

Shioda S: Reduced postischemic apoptosis in the hippocampus of mice deficient in interleukin-1.

Shioda S: Suppression of oxidative neuronal damage after transient middle cerebral artery occlusion in mice lacking interleukin-1. Neurosci Res

Stem/progenitor cells from bone marrow decrease neuronal death in global ischemia by modulation of inflammatory/immune responses. Proc Natl Acad Sci USA

Steroids and spinal cord injury: revisiting

Tamoxifen alleviates irradiation-induced brain injury by attenuating microglial inflammatory response in vitro and in vivo. Brain Res

TH: Neuroprotective effect of Scutellaria baicalensis on spinal cord injury in rats.

The bright side of the glial scar in CNS repair. Nat Rev Neurosci

The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol

The many faces of macrophage activation.

Ting JP: TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination. Nat Neurosci

UK: Microglial phenotype: is the commitment reversible? Trends Neurosci

Yoles E: Features of skin-coincubated macrophages that promote recovery from spinal cord injury.

Yong VW: Characterization of the early neuroinflammation after spinal cord injury in mice.

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3353190

Interleukin-1 participates in the classical and alternative activation of microglia/macrophages after spinal cord injury

Abstract

Similar works

Full text

Available Versions

Springer - Publisher Connector

Springer - Publisher Connector