Warren Samuels was an influential proponent of methodological pluralism in economics. This short paper discusses his understanding of methodological pluralism, and argues that it is based on three distinct components: (1) his critique of the idea that theories have epistemic foundations and his \u27matrix approach to meaningfulness,\u27 (2) his belief that the absence of meta-principles for science combined with our human psychology create an existential dilemma for theorists and policy-makers, and (3) his understanding of relativism, social constructivism, and \u27limited but affirmative\u27 defense of nihilism against the charge of skepticism. The paper closes with a brief discussion of what Samuels\u27 methodological pluralism might tell us about historiography and the history of economics
