Albrektsson BE

Astephen Wilson JL

Bart G Pijls

Bart L Kaptein

Bloebaum RD

Carlsson A

Cross MJ

Devereaux PJ

Dunbar MJ

Edward R Valstar

Epinette J. A

Ewald FC

Geesink RG

Grewal R

Henricson A

Holm S

Insall JN

Kaptein BL

Marta Fiocco

Moher D

Nelissen RG

Nilsson KG

Onsten I

Overgaard S

Pijls BG

Regner L

Rob GHH Nelissen

Ryd L

Soballe K

Sugimoto K

Therbo M

Toksvig-Larsen S

Valstar ER

Voigt JD

Acta Orthopaedica

English

PubMed

Optimising joint reconstruction management in arthritis and bone tumour patient

Pijls, B.G.

Valstar, E.R.

Kaptein, B.L.

Fiocco, M.

Nelissen, R.G.H.H.

Leiden University Scholary Publications

The beneficial effect of hydroxyapatite lasts A randomized radiostereometric trial comparing hydroxyapatite-coated, uncoated, and cemented tibial components for up to 16 years

NARCIS 

Crossref

The beneficial effect of hydroxyapatite lasts

Background and purpose In contrast to early migration, the long-term migration of hydroxyapatite- (HA-) coated tibial components in TKA has been scantily reported. This randomized controlled trial investigated the long-term migration measured by radiostereometric analysis (RSA) of HA-coated, uncoated, and cemented tibial components in TKA. Patients and methods 68 knees were randomized to HA-coated (n = 24), uncoated (n = 20), and cemented (n = 24) components. All knees were prospectively followed for 11-16 years, or until death or revision. RSA was used to evaluate migration at yearly intervals. Clinical and radiographic evaluation was according to the Knee Society system. A generalized linear mixed model (GLMM, adjusted for age, sex, diagnosis, revisions, and BMI) was used to take into account the repeated-measurement design. Results The present study involved 742 RSA analyses. The mean migration at 10 years was 1.66 mm for HA, 2.25 mm for uncoated and 0.79 mm for the cemented group (p < 0.001). The reduction of migration by HA as compared to uncoated components was most pronounced for subsidence and external rotation. 3 tibial components were revised for aseptic loosening (2 uncoated and 1 cemented), 3 for septic loosening (2 uncoated and 1 cemented), and 1 for instability (HA-coated). 2 of these cases were revised for secondary loosening after a period of stability: 1 case of osteolysis and 1 case of late infection. There were no statistically significant differences between the fixation groups regarding clinical or radiographic scores. Interpretation HA reduces migration of uncemented tibial components. This beneficial effect lasts for more than 10 years. Cemented components showed the lowest migration. Longitudinal follow-up of TKA with RSA allows early detection of secondary loosening.Optimising joint reconstruction management in arthritis and bone tumour patient

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The beneficial effect of hydroxyapatite lasts: A randomized radiostereometric trial comparing hydroxyapatite-coated, uncoated, and cemented tibial components for up to 16 years

The beneficial effect of hydroxyapatite lasts: A randomized radiostereometric trial comparing hydroxyapatite-coated, uncoated, and cemented tibial components for up to 16 years

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Leiden University Scholary Publications

Leiden University Scholary Publications

NARCIS

Crossref

Leiden University Scholary Publications