Presnovne spremembe pri kaheksiji povzročajo pospešeno izgubo funkcionalnih tkiv v telesu, predvsem so prizadete mišice. Nezadostna telesna aktivnost in podhranjenost telesno propadanje še pospešujeta. Učinki vadbe pri bolnikih z rakom tako kot pri drugih kroničnih bolnikih neposredno zmanjšujejo negativen vpliv bolezni na telo. Z redno telesno vadbo v aerobnem območju se povečujejo funkcionalne sposobnosti obtočil, srca, mišic in presnovnih procesov, ki vodijo do večje vzdržljivosti telesa. Z vajami za moč pa se vzdržuje zmogljivost mišic in zavira njihovo propadanje.Telesna vadba naj bo redna, 3- do 5-krat na teden. Če je bolnik močno presnovno iztirjen in ima hudo prizadet imunski sistem, telesne vadbe ne priporočamo.Cachexia-induced metabolic changes stimulate an enhanced loss of functional tissue in human body, particularly muscles. Inadequate physical activity and undernourishment further increase the loss of tissue. In cancer patients as well as in chronic patients, physical activity inhibits straightforwardly the negative effect of the disease on the body organs. Regular aerobic exercise enhances functional capacity of blood circulation, heart, muscles and metabolic processes, which help to sustain better physical condition. The strength training exercises help to maintain the muscles in good condition, thereby inhibiting their weakening. Physical exercises should be regularly performed, at least 3 to 5 times per week. A patient with derailed metabolism or severely impaired immune system is not advised to perform exercises
