Objectives: The incidence of thyroid cancer is increasing in several countries. The main aim of this study was to find and describe province-specific estimates of incidence in males and females by age groups for thyroid cancer. Methodology: The data used in this study were collected from a cancer registry that was established by Health Deputy of Golestan province for a period of one year (2004), in different age groups. Thyroid cancer data was identified and collected through the eighteen Pathology Laboratory centers (where males and female populations is referred) in Golestan province. Results: A total of 348 females and 409 males cases with cancer representing all sites were identified during the study period. It included seventeen females and five male thyroid cancer patients. In female's thyroid cancer, there were twelve papillary carcinoma (70.6%), two medullary carcinoma, one carcinoma anaplastic and one carcinoma (5.9%). In male's, there were two papillary carcinoma (40%) and one follicular carcinoma. The incidence of thyroid cancer in 70-79 age groups for females and males was the highest and lowest in age group 10-19 years' in females and 30-39 years in males. Conclusion: The incidence of thyroid cancer is higher in females when compared with males as per this one year study. However since this is just one year data, it needs to be studied further to confirm these findings
