Recent emergence of infections resulting from this strain is of public health concern

Alice Wong

Andrew E. Simor

Barrangou

Bhat

Brouns

Christianson

de Neeling

Denise Gravel

Enright

Gary Van Domselaar

George R. Golding

Gibbs

Godde

Golding

Grissa

Harmsen

John Wylie

Khanna

Kondo

Krziwanek

Kunin

Louis Bryden

Marraffini

McDonald

Meyer

Michael R. Mulvey

Monecke

Morag R. Graham

Mulvey

Paul N. Levett

Ryan R. McDonald

Schwarz

Shaun Tyler

Simor

Skov

Smith

van Duijkeren

van Loo

van Rijen

Voss

Walther

Witte

Wulf

Zhang

Emerging Infectious Diseases

English

PubMed

Crossref

Livestock-associated Methicillin-Resistant
                    Staphylococcus aureus

Rates of colonization with livestock-associated methicillin-resistant Staphylococcus aureus (MRSA) sequence type 398 have been high for pigs and pig farmers in Canada, but prevalence rates for the general human population are unknown. In this study, 5 LA-MRSA isolates, 4 of which were obtained from skin and soft tissue infections, were identified from 3,687 tested MRSA isolates from persons in Manitoba and Saskatchewan, Canada. Further molecular characterization determined that these isolates all contained staphylococcal cassette chromosome (SCC) mecV, were negative for Panton-Valentine leukocidin, and were closely related by macrorestriction analysis with the restriction enzyme Cfr91. The complete DNA sequence of the SCCmec region from the isolate showed a novel subtype of SCCmecV harboring clustered regularly interspaced short palindromic repeats and associated genes. Although prevalence of livestock-associated MRSA seems to be low for the general population in Canada, recent emergence of infections resulting from this strain is of public health concern

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Livestock-associated Methicillin-Resistant Staphylococcus aureus Sequence Type 398 in Humans, Canada

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Livestock-associated Methicillin-Resistant Staphylococcus aureus Sequence Type 398 in Humans, Canada

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