Horiba, Yuko

Koike, Hiroshi

Watanabe, Kenji

Yoshino, Tetsuhiro

Elsevier - Publisher Connector 

Characteristics of Patients with Cancer Treated with Japanese Kampo Medicine 

81 ICCMR 2015 Poster Presentation Abstracts
P2.010
A systematic review and meta-analysis on
the safety of yoga
Holger Cramer1, Lesley Ward2,
Robert Saper3, Daniel Fishbein4,
Gustav Dobos1, Romy Lauche1
1 Department of Internal and Integrative Medicine,
University of Duisburg-Essen, Essen, Germany
2 Dunedin School of Medicine, University of Otago,
Dunedin, New Zealand
3 Boston University School of Medicine, Boston,
MA, USA
4 Myanmar Research International, Santa Barbara,
CA, USA
Purpose: To systematically assess and meta-analyze the
frequency of adverse events in randomized controlled trials
of yoga.
Methods: Medline/Pubmed, Scopus, Cochrane Library,
IndMED and tables of content of yoga specialty journals not
listed inmedical databaseswere screened from their inception
until February 2014. Randomized controlled trials compar-
ing yoga to other interventions, and reporting non-serious
adverse events, serious adverse events, intervention-related
adverse events, and/or drop-outs due to adverse events were
included. Study characteristics and risk of bias (Cochrane risk
of bias tool) were assessed by 2 reviewers independently. Risk
differences (RD), odds ratios (OR), and their respective 95%
conﬁdence intervals (CI) were calculated and meta-analyzed
using a random effects model.
Results: Out of 2,520 initially identiﬁed records, 301 were
randomized controlled trials of yoga, of which 94 (total of
8,430 participants) reported on adverse events. No differences
in the frequency of non-serious, serious, or intervention-
related adverse events and of drop-outs due to adverse
events were found when comparing yoga to usual care or
exercise. Compared to psychological or educational interven-
tions, more non-serious adverse events (RD=0.11; 95% CI=0.02,
0.19; p=0.01; OR=7.29; 95% CI=1.91, 27.89; p<0.01) and more
intervention-related adverse events (RD=0.05; 95%CI=-0.02,
0.12; p=0.10; OR=4.72; 95% CI=1.01, 21.99; p=0.05) occurred in
the yoga group; serious adverse events and drop-outs due to
adverse events were comparable between groups.
Conclusion:Only 31% of the identiﬁed randomized trials of
yoga reported on adverse events. While non-serious adverse
events are more frequent with yoga than with psychological
interventions, yoga appears as a generally safe intervention,
comparable to exercise and usual care. Despite the limita-
tions of the available evidence, recommending yoga to healthy
people and those with underlying illnesses should not be dis-
couraged based on safety and can be considered if sufﬁcient
evidence of effectiveness is available.
Contact:HolgerCramer, h.cramer@kliniken-essen-mitte.de
http://dx.doi.org/10.1016/j.imr.2015.04.119
P2.011
Characteristics of Patients with Cancer
Treated with Japanese Kampo Medicine
Hiroshi Koike, Tetsuhiro Yoshino,
Yuko Horiba, Kenji Watanabe
Center for Kampo Medicine, Keio University School
of Medicine
Purpose: In Japan, cancer patients demand Kampo treat-
ment, in order to augment the immune system or ameliorate
the side effects from anti cancer therapy such as chemother-
apy or irradiation. Here we report the characteristics of
cancer-bearing patients in Kampo clinic.
Methods: Patients who made their ﬁrst visit to the center
for Kampo medicine at Keio University Hospital between May
2008 and March 2013 were included in this study. We counted
and examined the patients who suffered from cancer in 4,057
patients (2,928 women, 72%).
Results: We treated 211 cancer patients (132 women, 63%.
average age 59±14) in Kampo clinic. The patients consulted for
the purpose of enhancement of immunity for cancer, improve-
ment of cancer-related symptoms, or reduction of side effects
of anti-cancer therapy. The patients with cancer were 5% of all
patients. Among male patients, largest population was in the
60’s and in the 50’s among female patients. In male patients,
14% of patients suffered from colon cancer, also 14% from lung
cancer, 11% from prostate cancer, 10% from stomach cancer
and 9% from pancreas cancer. Among female patients, 39%
suffered from breast cancer, 18% from uterus cancer, 9% from
colon cancer, 8% from lung cancer and also 8% from stomach
cancer.
Conclusion: We showed that our patients suffered from
cancers of various types. In the Japanese national surveil-
lance, largest population of cancer patients is in the 70’s in
both men and women. The average age of the cancer patients
treated with Kampo medicine was younger than the Japanese
national surveillance. There were more patients with cancer
of prostate, breast or uterine, compared with the Japanese
national surveillance. Japanese doctors can use both Western
and Kampo medicines in one medical institute with public
health insurance. Cancer patients can use combination ther-
apies with Western and Kampo medicines easily in Japan.
Contact: Hiroshi Koike, koike-h@umin.org
http://dx.doi.org/10.1016/j.imr.2015.04.120


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Characteristics of Patients with Cancer Treated with Japanese Kampo Medicine

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