Alley, Katelyn

Cunneen, Quinn

Prieto, Dario

English

Digital Commons @ Montana Tech

Montana Tech Library Digital Commons @ Montana Tech TECHxpo Student Scholarship Spring 4-13-2020 Catalytic Neutralization of Organophosphate Simulant Over Undercoordinated Fe, Cu, Co, and Zn on SiO2 Quinn Cunneen Katelyn Alley Dario Prieto Follow this and additional works at: https://digitalcommons.mtech.edu/techxpo Catalytic neutralization of organophosphate simulant over undercoordinated Fe, Cu, Co, and Zn on SiO2  Quinn Cunneen (BS Chem. ‘20), Katelyn Alley (BS Chem. ‘21), Dario Prieto Applied Surface Science Laboratory Mechanical Engineering Department Montana Technological University, Butte, MT 59701  Background   Organophosphates (OP) inhibit nor-mal breakdown of neurotransmitters  Zn dimers, Zr clusters neutralize OP by hydrolyzing its best leaving group Hypothesis Low-coordination transition metals  on SiO2 will catalyze the hydrolysis of OP  3 potential reactions; a & b preferred  Simple, versatile, and scalable preparation of catalysts and precursors References  Dumas, et al.. Arch. Biochem. Biophys. 277, 155–159 (1990).  Katz, et al. Angew. Chemie 126, 507–511 (2014).  Mondloch, et al. Nat. Mater. 14, 512–516 (2015).  Wang, et al. Nat. Protoc. 11, 149–162 (2015).  Platero-Prats, et al. J. Am. Chem. Soc. 138, 4178–4185 (2016).  Haldoupis, et al. J. Am. Chem. Soc. 132, 7528–7539 (2010).  van Dillen, et al. J. Catal. 216, 257–264 (2003). This research was sponsored by the           Combat Capabilities Development Command Army Research Laboratory                            and was accomplished under                         Cooperative Agreement Number           W911NF-15-2-0020 EDTA promotes metal dispersion               Higher dispersion relative to M-nitrates  EDTA mass loss correlates to loading               Ligand mass loss as metal loading proxy   Metal loadings of 0.6–2.4 wt%  Surface density of 0.16–0.64 nm-2  Instruments  TA Instruments TA500   Agilent Cary60 + Pike Tech DiffusIR SiO2 from Fe(NO3)3  from FeEDTA  from Cu(NO3)2  from CuEDTA  from CoEDTA   Catalytic OP neutralization w/ H2O2               No reaction without H2O2  No activity-precursor relations  No selectivity-precursor relations  ~ 1-to-1 reaction a to reaction b  Activity increases Co = Fe < Zn < Cu Homogeneous reaction of OP with •OH  Instrument Shimadzu GC2030-FID/NPD a b c 3.5 ml MeCN 1.0 ml 30% H2O2 0.5 ml Malathion 100 mg Catalyst T = 60 oC 

Catalytic Neutralization of Organophosphate Simulant Over Undercoordinated Fe, Cu, Co, and Zn on SiO2

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Catalytic Neutralization of Organophosphate Simulant Over Undercoordinated Fe, Cu, Co, and Zn on SiO2

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