This DNP project examined the effect of unit case reports and individualized nurse report cards on nurses’ awareness of and attitudes toward central line-associated bloodstream infection (CLABSI) contributing factors. This project also sought to determine whether CLABSI incidences differed across units and if that was affected by nurses’ awareness of and attitudes toward CLABSI contributing factors. A convenience sample of registered nurses (RNs) across four medical units was included in this project. Of the 79 RNs who participated in providing feedback on this project, 48 RNs completed pre-implementation surveys, resulting in a response rate of 61%, and 53 completed post-implementation surveys resulting in a response rate of 67%. CLABSI RN Awareness and Attitudes pre- and post-implementation survey responses were compared using descriptive and inferential statistics. The analysis found no significant differences between pre-implementation and post-implementation survey responses and no significant differences between post-implementation responses across units. Included is a discussion on notable findings related to staff perceived readiness and receptiveness to the project intervention and implications for future study