B Cudia

B Napoli

C Zemlin

E Bonafede

F P Palumbo

G Diana

M Mangiapane

M Pera

P Zoellner

S Serantoni

BMC Geriatrics

English

PubMed

Palumbo, FP

Serantoni, S

Pera, M

Bonafede, E

Mangiapane, M

CUDIA, Bianca Maria

DIANA, Giuseppe

Archivio istituzionale della ricerca - Università di Palermo

MEETING ABSTRACT Open AccessRole of a medication in polyurethane foam in thetreatment of diabetic foot lesionsF P Palumbo1*, S Serantoni2, M Pera3, E Bonafede1, M Mangiapane1, B Cudia1, G Diana1From de Senectute: Age and Health ForumCatanzaro, Italy. 5-7 December 2009BackgroundThe treatment of diabetic foot lesions need medicationscapable of managing wound infection and exudates that,variously combined, can influence the natural history ofthe pathology and therefore limb survival. A particularand economic device, is represented by honeycombstructure polyurethane foam Ligasano ©.Material and methodsWe evaluated 5 patients with a diabetic foot and a casehistory of infected wounds until flemmone. The lesionshave been debrided and/or surgically drained and thenmedicated three time a week, with variable thicknessLigasano (0,5 and 1 cm). Tissue sample was collected toperform colture and antibiogram. According to diabeticfoot guidelines of Consensus Conference 2003 patients(3 male and 2 female – mean age 54,3 years) wereaffected by skin lesions of the foot and were classified asin Table 1. Medications were performed until the reduc-tion and/or complete healing.ResultsThe patients have been medicated once a day for 10 days(2, 5) and/or once every three weeks (3/5) for the firsttwo months. The mean time of the treatment was of196 day for 4 patients. In 1 patient a minor cardiovascu-lar event occurred and time of therapy was 296 days.ConclusionsIn our experience the device was proved to be economicand manageable, allowing the management of the exu-dates and avoiding, at the same time, the involvement ofthe perilesional skin that constitutes itself an innovationon the treatment of diabetic foot lesion.1U.O. Chirurgia Geriatrica, A.O.U. Policlinico “Paolo Giaccone”, Palermo, ItalyFigure 1 Plantar lesion.Table 1Complications Number of patientsglycometabolic failure 4/5cardiovascular complications 3/5kidney disease 1/5rethinic disease 2/5Palumbo et al. BMC Geriatrics 2010, 10(Suppl 1):A71http://www.biomedcentral.com/1471-2318/10/S1/A71© 2010 Palumbo et al; licensee BioMed Central Ltd.Author details1U.O. Chirurgia Geriatrica, A.O.U. Policlinico “Paolo Giaccone”, Palermo, Italy.2Centro per la Diagnosi e la Terapia delle Ulcere Vascolari, Casa di Cura “VillaFiorita”, Prato, Italy. 3Centro per la Diagnosi e la Terapia delle UlcereVascolari, Casa di cura “San Camillo”, Versilia Righi, Viareggio, Italy.Published: 19 May 2010References1. Zoellner P, Kapp H, Smola H: A prospective, open-label study to assessthe clinical performance of a foam dressing in the management ofchronic wounds. Ostomy Wound manage 2006, 52(5):34-6.2. Napoli B, Benigno A, D’Arpa N, Amico M, Conte F: Local treatment ofburns with honeycomb expanded polyurethane (Ligasano). Annals ofBurns and Fire Disaster 2008, XXI n.1.3. Zemlin C: Studio sull’impiego di Ligasano come medicazione primarianelle lesioni del piede di origine diabetica. Ligamed 2008.doi:10.1186/1471-2318-10-S1-A71Cite this article as: Palumbo et al.: Role of a medication in polyurethanefoam in the treatment of diabetic foot lesions. BMC Geriatrics 201010(Suppl 1):A71.Figure 4 Flemmone of the left foot surgically drained and treated with antibiotic therapy and intracavitary Ligasano.Figure 3 Infected lesion with tendons exposure.Figure 2 Infected lesion of the dorsum of the foot onset because the patient wears unqualified shoe.Palumbo et al. BMC Geriatrics 2010, 10(Suppl 1):A71http://www.biomedcentral.com/1471-2318/10/S1/A71Page 2 of 2

Role of a medication in polyurethane foam in the treatment of diabetic foot lesions

Springer - Publisher Connector

MEETING ABSTRACT Open Access
Role of a medication in polyurethane foam in the
treatment of diabetic foot lesions
F P Palumbo1*, S Serantoni2, M Pera3, E Bonafede1, M Mangiapane1, B Cudia1, G Diana1
From de Senectute: Age and Health Forum
Catanzaro, Italy. 5-7 December 2009
Background
The treatment of diabetic foot lesions need medications
capable of managing wound infection and exudates that,
variously combined, can influence the natural history of
the pathology and therefore limb survival. A particular
and economic device, is represented by honeycomb
structure polyurethane foam Ligasano ©.
Material and methods
We evaluated 5 patients with a diabetic foot and a case
history of infected wounds until flemmone. The lesions
have been debrided and/or surgically drained and then
medicated three time a week, with variable thickness
Ligasano (0,5 and 1 cm). Tissue sample was collected to
perform colture and antibiogram. According to diabetic
foot guidelines of Consensus Conference 2003 patients
(3 male and 2 female – mean age 54,3 years) were
affected by skin lesions of the foot and were classified as
in Table 1. Medications were performed until the reduc-
tion and/or complete healing.
Results
The patients have been medicated once a day for 10 days
(2, 5) and/or once every three weeks (3/5) for the first
two months. The mean time of the treatment was of
196 day for 4 patients. In 1 patient a minor cardiovascu-
lar event occurred and time of therapy was 296 days.
Conclusions
In our experience the device was proved to be economic
and manageable, allowing the management of the exu-
dates and avoiding, at the same time, the involvement of
the perilesional skin that constitutes itself an innovation
on the treatment of diabetic foot lesion.
1U.O. Chirurgia Geriatrica, A.O.U. Policlinico “Paolo Giaccone”, Palermo, Italy
Figure 1 Plantar lesion.
Table 1
Complications Number of patients
glycometabolic failure 4/5
cardiovascular complications 3/5
kidney disease 1/5
rethinic disease 2/5
Palumbo et al. BMC Geriatrics 2010, 10(Suppl 1):A71
http://www.biomedcentral.com/1471-2318/10/S1/A71
© 2010 Palumbo et al; licensee BioMed Central Ltd.
Author details
1U.O. Chirurgia Geriatrica, A.O.U. Policlinico “Paolo Giaccone”, Palermo, Italy.
2Centro per la Diagnosi e la Terapia delle Ulcere Vascolari, Casa di Cura “Villa
Fiorita”, Prato, Italy. 3Centro per la Diagnosi e la Terapia delle Ulcere
Vascolari, Casa di cura “San Camillo”, Versilia Righi, Viareggio, Italy.
Published: 19 May 2010
References
1. Zoellner P, Kapp H, Smola H: A prospective, open-label study to assess
the clinical performance of a foam dressing in the management of
chronic wounds. Ostomy Wound manage 2006, 52(5):34-6.
2. Napoli B, Benigno A, D’Arpa N, Amico M, Conte F: Local treatment of
burns with honeycomb expanded polyurethane (Ligasano). Annals of
Burns and Fire Disaster 2008, XXI n.1.
3. Zemlin C: Studio sull’impiego di Ligasano come medicazione primaria
nelle lesioni del piede di origine diabetica. Ligamed 2008.
doi:10.1186/1471-2318-10-S1-A71
Cite this article as: Palumbo et al.: Role of a medication in polyurethane
foam in the treatment of diabetic foot lesions. BMC Geriatrics 2010
10(Suppl 1):A71.
Figure 4 Flemmone of the left foot surgically drained and treated with antibiotic therapy and intracavitary Ligasano.
Figure 3 Infected lesion with tendons exposure.
Figure 2 Infected lesion of the dorsum of the foot onset because the patient wears unqualified shoe.
Palumbo et al. BMC Geriatrics 2010, 10(Suppl 1):A71
http://www.biomedcentral.com/1471-2318/10/S1/A71
Page 2 of 2


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A prospective, open-label study to assess the clinical performance of a foam dressing in the management of chronic wounds. Ostomy Wound manage

Conte F: Local treatment of burns with honeycomb expanded polyurethane (Ligasano).

Studio sull’impiego di Ligasano come medicazione primaria nelle lesioni del piede di origine diabetica. Ligamed

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Role of a medication in polyurethane foam in the treatment of diabetic foot lesions

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