Background: Malaria is endemic in the Rajasthali region of the Chittagong Hill Tracts in Bangladesh and the Rajasthali region is the most endemic area of Bangladesh. Quantifying the role of environmental and socioeconomic factors in the local spatial patterns of malaria endemicity can contribute to successful malaria control and elimination. This study aimed to investigate the role of environmental factors on malaria risk in Rajasthali and to quantify the geographical clustering in malaria risk unaccounted by these factors

Glass, Gregory E

Haque, Rashidul

Haque, Ubydul

Kolivras, Korine N

Mitra, Dipak

Schmidt, Wolf-Peter

Soares Magalhães, Ricardo J

Malaria Journal

English

PubMed

Ubydul Haque

Ricardo J Soares Magalhães

Dipak Mitra

Korine N Kolivras

Wolf-Peter Schmidt

Rashidul Haque

Gregory E Glass

Springer - Publisher Connector

The role of age, ethnicity and environmental factors in modulating malaria risk in Rajasthali, Bangladesh

Soares Magalhães, Ricardo J.

Kolivras, Korine N.

Glass, Gregory E.

University of Queensland eSpace

Abstract Background Malaria is endemic in the Rajasthali region of the Chittagong Hill Tracts in Bangladesh and the Rajasthali region is the most endemic area of Bangladesh. Quantifying the role of environmental and socio-economic factors in the local spatial patterns of malaria endemicity can contribute to successful malaria control and elimination. This study aimed to investigate the role of environmental factors on malaria risk in Rajasthali and to quantify the geographical clustering in malaria risk unaccounted by these factors. Method A total of 4,200 (78.9%; N = 5,322) households were targeted in Rajasthali in July, 2009, and 1,400 individuals were screened using a rapid diagnostic test (Falci-vax). These data were linked to environmental and socio-economic data in a geographical information system. To describe the association between environmental factors and malaria risk, a generalized linear mixed model approach was utilized. The study investigated the role of environmental factors on malaria risk by calculating their population-attributable fractions (PAF), and used residual semivariograms to quantify the geographical clustering in malaria risk unaccounted by these factors. Results Overall malaria prevalence was 11.7%. Out of 5,322 households, 44.12% households were living in areas with malaria prevalence of ≥ 10%. The results from statistical analysis showed that age, ethnicity, proximity to forest, household density, and elevation were significantly and positively correlated with the malaria risk and PAF estimation. The highest PAF of malaria prevalence was 47.7% for third tertile (n = 467) of forest cover, 17.6% for second tertile (n = 467) of forest cover and 19.9% for household density >1,000. Conclusion Targeting of malaria health interventions at small spatial scales in Bangladesh should consider the social and socio-economic risk factors identified as well as alternative methods for improving equity of access to interventions across whole communities.</p

Haque Ubydul

Soares Magalhães Ricardo J

Mitra Dipak

Kolivras Korine N

Schmidt Wolf-Peter

Haque Rashidul

Glass Gregory E

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[http://portfolio.theglobalfund.org/en/Search/DocumentSearch#]. doi:10.1186/1475-2875-10-367 Cite this article as: Haque et al.: The role of age, ethnicity and environmental factors in modulating malaria risk in Rajasthali, Bangladesh.

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Altitude-dependent and -independent variations in Plasmodium falciparum prevalence in northeastern Tanzania. J Infect Dis

AW: Speciation and distribution of the members of the Anopheles punctulatus(Diptera: Culicidae) group in Papua New Guinea.

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GE: Malaria prevalence, risk factors and spatial distribution in a hilly forest area of Bangladesh. PLoS One

GE: Progress and challenges to control malaria in a remote area of Chittagong hill tracts,

GE: Spatial prediction of malaria prevalence in an endemic area of Bangladesh.

Haque R: Prevalence of anopheline species and their Plasmodium infection status in epidemic-prone border areas of Bangladesh.

HP: Spatial analysis of malaria incidence at the village level in areas with unstable transmission in Ethiopia.

Maheswary NP: Forest malaria in Bangladesh. II. Transmission by Anopheles dirus.

Malaria prevalence in endemic districts of Bangladesh. PLoS One

Maximum likelihood estimation of the attributable fraction from logistic models. Biometrics

Modern Epidemiology. 2 edition.

Rahman MR: Malaria in southeast Bangladesh: a descriptive study. Bangladesh Med Res Counc Bull

Schellenberg D: Age-patterns of malaria vary with severity, transmission intensity and seasonality in sub-Saharan Africa: a systematic review and pooled analysis. PLoS One

Snow RW: Estimating the global clinical burden of Plasmodium falciparum malaria in 2007. PLoS Med

Snow RW: Urbanization, malaria transmission and disease burden in Africa. Nat Rev Microbiol

Spatial epidemiology of Plasmodium vivax, Afghanistan. Emerg Infect Dis

Spatial variation of malaria incidence in young children from a geographically homogeneous area with high endemicity. J Infect Dis

Syed Masud A, Akramul I, Rashidul H: Mapping malaria risk in Bangladesh using bayesian geostatistical models. Am J Trop Med Hyg

T: Tackling malaria today. BMJ

Towards malaria elimination–a new thematic series.

Transmission heterogeneity and control strategies for infectious disease emergence. PLoS One

WHO: World malaria report 2010 World Health Organization,

Yamamoto T: The role of climate variability in the spread of malaria in Bangladeshi highlands. PLoS One

Zayeri F: Spatial modeling of malaria incidence rates in Sistan and Baluchistan province, Islamic Republic of Iran. Saudi Med J

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The role of age, ethnicity and environmental factors in modulating malaria risk in Rajasthali, Bangladesh

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