Since decades, researchers are seeking novel therapeutic strategies to cure and monitor diseases for personalized health care needs. Numerous successful efforts are being made to design and develop personalized NanoMedicine approach to cure diseases at target site with minimum or no adverse effects. The designing of novel nanomaterials, maximum binding with therapeutic agent, controlled navigation, on demand or sustained release of drug, good biocompatibility, and maximum therapeutic potentials are crucial for effective theranostic approaches. Numerous studies have been conducted to formulate NanoMedicine and testing its efficacy using various in-vitro models. Unfortunately, such therapeutic nanoformulations are not well-tested yet using pre-clinical or human models
