The aim of this secondary data analysis study was to examine the association between certain predictors and student’s mathematics achievement on two tests of the Woodcock Johnson III Academic Knowledge subtests: Applied Problems and Calculations. Results indicated that students with a diagnosis of emotional and behavioral disorders (EBD) had academic deficits in mathematics, and these deficits became larger over time. Data pertaining to mathematics academic achievement from the first two waves of the National Longitudinal Transition Study 2 (N = 420) were examined. The variables investigated to further explore academic achievement scores were gender, race/ethnicity, student’s school attended prior to the start of the study, and parent or guardian characteristics. Differences between gender and race/ethnicity are explained. Implications, limitations, and areas for future research are also presented