A government’s commitment to an adopted policy may be the first step that symbolizes its genuine intent to ameliorate the living conditions of its people, particularly the relevant and/or beneficial populations for which the policy was formulated. Ghana’s President J. A. Kufuor’s New Patriotic Party government ended decades of debate about improving the conditions of the vulnerable group of women and children by establishing the Ministry of Women and Children’s Affairs. This article argues that, in order for the Ghanaian government to sustain efforts to effectively improve the plight of this group, there should be systematic mechanisms that include effective collaboration via sustainable-development, learning-organization, and knowledge-management philosophies. The study provides lessons that have implications for developing economies