We introduce randomized time-bounded Kolmogorov complexity (rKt), a natural extension of Levin's notion [Leonid A. Levin, 1984] of Kolmogorov complexity. A string w of low rKt complexity can be decompressed from a short representation via a time-bounded algorithm that outputs w with high probability. This complexity measure gives rise to a decision problem over strings: MrKtP (The Minimum rKt Problem). We explore ideas from pseudorandomness to prove that MrKtP and its variants cannot be solved in randomized quasi-polynomial time. This exhibits a natural string compression problem that is provably intractable, even for randomized computations. Our techniques also imply that there is no n^{1 - epsilon}-approximate algorithm for MrKtP running in randomized quasi-polynomial time. Complementing this lower bound, we observe connections between rKt, the power of randomness in computing, and circuit complexity. In particular, we present the first hardness magnification theorem for a natural problem that is unconditionally hard against a strong model of computation